404356-64-5Relevant articles and documents
Studies in the total synthesis of heliquinomycinone: Proof of concept and assembly of a fully mature spirocyclization precursor
Qin, Donghui,Ren, Rex X.,Siu, Tony,Zheng, Changsheng,Danishefsky, Samuel J.
, p. 4709 - 4713 (2007/10/03)
A strategy for the synthesis of heliquinomycin, a selective helicase inhibitor, hinges on the spirocyclization of precursor 3. Naphthofuran 1 and aldehyde 2 were readily prepared and used in the synthesis of 3. The key steps in the total synthesis of heli