40451-67-0

Basic information

• Product Name: 1-Pyrrolidinecarboxamide,2-oxo-(9CI)
• Synonyms: 1-Pyrrolidinecarboxamide,2-oxo-(9CI)
• CAS NO: 40451-67-0
• Molecular Formula: C₅H₈N₂O₂
• Molecular Weight: 128.13
• Product Categories: AMIDE
• Mol File: 40451-67-0.mol
• Article Data: 9

Chemical Properties

• Melting Point: 143-144 °C(Solv: benzene (71-43-2))
• Boiling Point: 250.7 °C at 760 mmHg
• Flash Point: 105.4 °C
• Appearance: /
• Density: 1.353 g/cm³
• Vapor Pressure: 0.0213mmHg at 25°C
• Refractive Index: 1.551
• PKA: 13.82±0.20(Predicted)
• CAS DataBase Reference: 1-Pyrrolidinecarboxamide,2-oxo-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxamide,2-oxo-(9CI)(40451-67-0)
• EPA Substance Registry System: 1-Pyrrolidinecarboxamide,2-oxo-(9CI)(40451-67-0)

Safety Data

• Hazardous Substances Data: 40451-67-0(Hazardous Substances Data)

Usage

Also known as

Succinimide (a common name for the compound)

Structure

Cyclic amide with a five-membered ring, including a carbonyl group and a nitrogen atom (described as a cyclic compound with specific functional groups)

Applications

Production of pharmaceuticals, as a plasticizer, as a pesticide, and as a chemical intermediate in organic chemistry reactions (indicating its versatility in various industries)

Properties

Studied for its potential anti-inflammatory and anticonvulsant properties (suggesting possible uses in medicine)

InChI:InChI=1/C5H8N2O2/c6-5(9)7-3-1-2-4(7)8/h1-3H2,(H2,6,9)

Upstream product

• 167417-31-4 1-(N-chloroacetylcarbamoyl)-2-pyrrolidinone 
• 590-28-3 potassium cyanate 
• 56-12-2 4-amino-n-butyric acid 
• 1411984-04-7 methyl 4-cyanamidobutanoate 
• 616-45-5 2-pyrrolidinon 
• 598-55-0 methyl carbamate 
• 75548-99-1 tetrahydro-2H-1,3-diazepine-2,4(3H)-dione 
• 57-13-6 urea 
• 2609-10-1 grateloupine 

Downstream Products

• 133861-85-5 BTMI 
• 103772-04-9 N-carbamoyl-2-methoxypyrrolidine 

Relevant articles and documents

Cyclization of 4-ureidobutanoic acids in acetic anhydride

A simple method is proposed for synthesizing 1-carbamoyl-2-pyrrolidones by cyclization of 4-ureidobutanoic acids in acetic anhydride.

Dibutylphosphate (DBP) mediated synthesis of cyclic N,N′- disubstituted urea derivatives from amino esters: A comparative study

The N,N′-disubstituted urea derivatives such as amino acid hydantoins and dihydrouracil derivatives were prepared starting from natural and unnatural amino acid esters using dibutylphosphate (DBP). During the attempted synthesis of N-heterocycles with larger than six-membered rings containing the N,N′-disubstituted urea functionalities, three unexpected products namely squamolone, N-methyl pyrrolidine-2-one, and diketopiperazine were isolated.

Process for preparing derivatives of isopropenyl-α, α-dimethylbenzyl isocyanate

A process for preparing blocked derivatives of m- or p- isopropenyl-α,α-dimethylbenzyl isocyanates, comprising reacting a meta- or a para-isopropenyl-α,α-dimethylbenzyl carbamate ester with hydroxy functional blocking group, such as hydroxyethylene-ethyleneurea, hydroxyethylenepropylene urea, dialkylaminoethanol and dialkylamino propanol