40473-50-5

Basic information

• Product Name: Benzenemethanol, 2-hydroxy-a-phenyl-
• CAS NO: 40473-50-5
• Molecular Formula: C13H12O2
• Molecular Weight: 200.237
• Mol File: 40473-50-5.mol
• Article Data: 41

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 2-hydroxy-a-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2-hydroxy-a-phenyl-(40473-50-5)
• EPA Substance Registry System: Benzenemethanol, 2-hydroxy-a-phenyl-(40473-50-5)

Safety Data

• Hazardous Substances Data: 40473-50-5(Hazardous Substances Data)

Upstream product

• 59648-27-0 2,4-diphenyl-1,3,2-benzodioxaborin 
• 117-99-7 2-Hydroxybenzophenone 
• 89-95-2 2-methyl-benzyl alcohol 
• 100-59-4 phenylmagnesium chloride 
• 90-02-8 salicylaldehyde 
• 108-95-2 phenol 
• 67-56-1 methanol 
• 100-58-3 phenylmagnesium bromide 
• 591-51-5 phenyllithium 
• 108-86-1 bromobenzene 
• 3117-37-1 3-phenyl-3H-benzofuran-2-one 
• 95-56-7 2-hydroxybromobenzene 
• 100-52-7 benzaldehyde 

Downstream Products

• 102102-95-4 (2R,3R,4S)-2-Ethoxy-3-methyl-4-phenyl-chroman 
• 102102-95-4 (2S,3S,4S)-2-Ethoxy-3-methyl-4-phenyl-chroman 
• 84095-63-6 2,2-Diethoxy-4-phenyl-chroman 
• 60027-87-4 trans-2-ethoxy-4-phenylchroman 
• 60027-87-4 cis-2-ethoxy-4-phenylchroman 
• 84095-64-7 2,2-Diethoxy-3-methyl-4-phenyl-chroman 
• 60027-87-4 2-ethoxy-4-phenylchroman 
• 3117-37-1 3-phenyl-3H-benzofuran-2-one 
• 28994-41-4 o-Benzylphenol 
• 55190-55-1 o-Hydroxybenzhydrylmethylether 
• 102078-84-2 N-(2-hydroxy-benzhydryl)-benzamide 
• 1245449-11-9 1-(2-(methylthio)-4-phenyl-4H-chromen-3-yl)ethanone 
• 1245449-02-8 2-(methylthio)-4-phenyl-4H-chromene-3-carbonitrile 
• 57049-58-8 3-phenyl-2,3-dihydrobenzofuran 

Relevant articles and documents

Organic Br?nsted acid-catalyzed cycloadditions of o-quinone methides with 1, 3-dicarbonlys: Facile access to xanthenones and chromanones

The in-situ generation of o-quinone methides and their inverse-electron-demand Diels–Alder reaction in the presence of pentacarboxycyclopentadiene—an organic Br?nsted acid—has been reported. The synthesis of xanthenones and chromanones in good to excellen

Catalytic Asymmetric Three-component Hydroacyloxylation/ 1,4-Conjugate Addition of Ynamides

A highly enantioselective three-component hydroacyloxylation/1,4-conjugate addition of ortho-hydroxybenzyl alcohols, ynamides and carboxylic acids was developed under mild reaction conditions in the presence of a chiral N,N′-dioxide/Sc(OTf)3 complex, which went through in situ generated ortho-quinone methides with α-acyloxyenamides, delivering a range of corresponding chiral α-acyloxyenamides derivatives containing gem(1,1)-diaryl skeletons in moderate to good yields with excellent ee values. The scale-up experiment and further derivation showed the practicality of this catalytic system. In addition, a possible catalytic cycle and transition state model was proposed to elucidate the origin of the stereoselectivity based on X-ray crystal structure of the α-acyloxyenamide intermediate and product.

Regio- A nd Enantioselective Friedel-Crafts Benzhydrylation of Indoles in Carbocyclic Ring with ortho-Quinomethanes: Access to Chiral Diarylindolylmethanes

The functionalization of indoles in the carbocyclic ring has been achieved via organocatalytic enantioselective Friedel-Crafts benzhydrylation of hydroxyindoles with in situ generated ortho-quinomethanes in oil-water biphases, allowing an efficient access to varied diarylindolylmethanes with a wide substrate scope. The high yields, excellent stereoselectivities, mild conditions, low catalyst loading, and easy scalability also demonstrated the interest of this novel methodology.