404859-21-8

Basic information

• Product Name: 1H-Isoindol-1-one, 3-methyl- (9CI)
• Synonyms: 1H-Isoindol-1-one, 3-methyl- (9CI);3-Methyl-1H-Isoindol-1-one
• CAS NO: 404859-21-8
• Molecular Formula: C9H7NO
• Molecular Weight: 145.15798
• Product Categories: ALCOHOL
• Mol File: 404859-21-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Isoindol-1-one, 3-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindol-1-one, 3-methyl- (9CI)(404859-21-8)
• EPA Substance Registry System: 1H-Isoindol-1-one, 3-methyl- (9CI)(404859-21-8)

Safety Data

• Hazardous Substances Data: 404859-21-8(Hazardous Substances Data)

Relevant articles and documents

Iron-catalyzed stereoselective haloamidation of amide-tethered alkynes

In this work, by usingN-methoxybenzamides as efficient acyl nitrene precursors, an iron-catalyzed formalcis-haloamidation of alkyne is reported. Without assistance of additives, the reaction worked well in the presence of 50 mol% FeCl3or FeBr3, leading to a series of chloro/bromo-containing isoindolin-5-ones with high efficiency and wide reaction scope. In the reaction, the iron-facilitated haloamidation proceeds through a halo anion-participating concerted [3+2] cyclization to release the final products. The key intermediate ferric acyl nitreneAis generatedin situfrom a formal removal of MeOH.