405154-52-1

Basic information

• Product Name: 2-amino-3-(2-(2-hydroxyphenyl)benzo[d]oxazol-5-yl)propanoic acid
• Synonyms: 2-amino-3-(2-(2-hydroxyphenyl)benzo[d]oxazol-5-yl)propanoic acid
• CAS NO: 405154-52-1
• Molecular Weight: 298.298
• Mol File: 405154-52-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-amino-3-(2-(2-hydroxyphenyl)benzo[d]oxazol-5-yl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-3-(2-(2-hydroxyphenyl)benzo[d]oxazol-5-yl)propanoic acid(405154-52-1)
• EPA Substance Registry System: 2-amino-3-(2-(2-hydroxyphenyl)benzo[d]oxazol-5-yl)propanoic acid(405154-52-1)

Safety Data

• Hazardous Substances Data: 405154-52-1(Hazardous Substances Data)

Upstream product

• 444-30-4 2-(trifluoromethyl)phenol 
• 3387-86-8 3-amino-tyrosine 

Relevant articles and documents

Transformation of anionically activated trifluoromethyl groups to heterocycles under mild aqueous conditions

The (hetero)aromatic trifluoromethyl group is present in many biologically active molecules and is generally considered to be chemically stable. In this paper, a convenient one-step synthesis of C-C linked aryl-heterocycles or heteroaryl-heterocycles in good to excellent yields via the reaction of anionically activated trifluoromethyl groups with amino nucleophiles containing a second NH, OH, or SH nucleophile in 1 N sodium hydroxide is reported. The method has high functional group tolerability and is potentially useful in parallel synthesis.