40545-33-3

Basic information

• Product Name: 2-AMINO-5-METHYLBENZAMIDE
• Synonyms: 2-AMINO-5-METHYLBENZAMIDE;Benzamide, 2-amino-5-methyl- (9CI);Benzamide, 2-amino-5-methyl-
• CAS NO: 40545-33-3
• Molecular Formula: C₈H₁₀N₂O
• Molecular Weight: 150.18
• Product Categories: AMIDE;AMINEPRIMARY
• Mol File: 40545-33-3.mol
• Article Data: 25

Chemical Properties

• Melting Point: 178-180°C
• Boiling Point: 265.7°C at 760 mmHg
• Flash Point: 114.5°C
• Appearance: /
• Density: 1.185g/cm³
• Vapor Pressure: 0.009mmHg at 25°C
• Refractive Index: 1.615
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 15.88±0.50(Predicted)
• CAS DataBase Reference: 2-AMINO-5-METHYLBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5-METHYLBENZAMIDE(40545-33-3)
• EPA Substance Registry System: 2-AMINO-5-METHYLBENZAMIDE(40545-33-3)

Safety Data

• Statements: 36/37/38-36
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 40545-33-3(Hazardous Substances Data)

Usage

General Description

2-AMINO-5-METHYLBENZAMIDE is a chemical compound with the molecular formula C8H10N2O. It is a derivative of benzamide, with a methyl group attached to the nitrogen atom. This chemical is a white solid at room temperature and is soluble in organic solvents. 2-AMINO-5-METHYLBENZAMIDE is commonly used as a building block in the synthesis of pharmaceuticals and other organic compounds. It has potential applications in the development of drugs for various medical conditions. Its chemical properties and structure make it a versatile and valuable compound in the field of organic chemistry.

InChI:InChI=1/C8H10N2O/c1-5-2-3-7(9)6(4-5)8(10)11/h2-4H,9H2,1H3,(H2,10,11)

Upstream product

• 4315-12-2 5-methyl-2-nitrobenzamide 
• 608-05-9 5-methyl-indole-2,3-dione 
• 5925-93-9 2-amino-5-methylbenzonitrile 
• 38818-49-4 5-methyl-2-nitrobenzoyl chloride 
• 2941-78-8 2-Amino-5-methylbenzoic acid 
• 530-62-1 1,1'-carbonyldiimidazole 
• 79-37-8 oxalyl dichloride 
• 3113-72-2 5-methyl-2-nitrobenzoic acid 
• 620-22-4 3-Methylbenzonitrile 
• 4692-99-3 6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 
• 64113-86-6 2-nitro-5-methylbenzonitrile 

Downstream Products

• 263713-35-5 2-amino-5-methylbenzylamine 
• 1448462-24-5 (E)-2-(3-(2-methoxyphenyl)acrylamido)-5-methylbenzamide 
• 1448462-30-3 5-methyl-2-(3-phenylpropiolamido)benzamide 
• 1448462-34-7 5-methyl-2-(3-phenylpropanamido)benzamide 
• 112253-73-3 2-azido-5-bromo-5'-methyl-2'-carboxamidobenzanilide 
• 112253-74-4 2-azido-5'-methyl-2'-carboxamidobenzanilide 
• 600718-11-4 6-methyl-3-phenyl-4(3H)-quinazolinone-2-ylmercaptoacetic acid ethyl ester 
• 21419-51-2 6-methyl-2-phenylquinazolin-4(3H)-one 
• 82256-07-3 6-methyl-2-(4-methylphenyl)-4(3H)-quinazolinone 

Relevant articles and documents

COMBINATION THERAPY FOR TREATING MPS1

The application is directed to compounds of formula (I) and their salts and solvates, wherein B, R1, R2, R3, R3', R4, R4', and R5 are as set forth in the specification, as well as to methods for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or prevention of, e.g., MPS1, optionally in combination with α-L-iduronidase or an analog or variant thereof, e.g., laronidase.

Trash to treasure: Eco-friendly and practical synthesis of amides by nitriles hydrolysis in WepPA

The hydration of nitriles to amides in a water extract of pomelo peel ash (WEPPA) was realized with moderate to excellent yields without using external transition metals, bases or organic solvents. This reaction features a broad substrate scope, wide functional group tolerance, prominent chemoselectivity, and good reusability. Notably, a magnification experiment in this bio-based solvent at 100 mmol further demonstrated its practicability.

POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS

The present invention is related to a pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent and a compound represented by the following structural formula: The present invention is also related a method of treating a subject with a disease which can be ameliorated by inhibition of poly(ADP-ribose)polymerase (PARP). The definitions of the variables are provided herein.