40630-82-8

Basic information

• Product Name: ALLYL 2-BROMO-2-METHYLPROPIONATE
• Synonyms: ALLYL 2-BROMO-2-METHYLPROPIONATE;Allyl α-bromoisobutyrate;Allyl 2-broMo-2-Methylpropionate 98%;Propanoic acid, 2-bromo-2-methyl-, 2-propenyl ester
• CAS NO: 40630-82-8
• Molecular Formula: C₇H₁₁BrO₂
• Molecular Weight: 207.07
• Product Categories: Allyl Monomers;Monomers;Polymer Science
• Mol File: 40630-82-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 50-51 °C12 mm Hg(lit.)
• Flash Point: 147 °F
• Appearance: /
• Density: 1.302 g/mL at 25 °C(lit.)
• Vapor Pressure: 2.68mmHg at 25°C
• Refractive Index: n20/D 1.462(lit.)
• CAS DataBase Reference: ALLYL 2-BROMO-2-METHYLPROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: ALLYL 2-BROMO-2-METHYLPROPIONATE(40630-82-8)
• EPA Substance Registry System: ALLYL 2-BROMO-2-METHYLPROPIONATE(40630-82-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-27-36/37/39
• RIDADR: UN 3334
• WGK Germany: 3
• Hazardous Substances Data: 40630-82-8(Hazardous Substances Data)

Usage

General Description

ALLYL 2-BROMO-2-METHYLPROPIONATE is a chemical compound with the molecular formula C6H11BrO2. It is a colorless liquid with a pungent odor, commonly used as a reagent in organic synthesis and chemical reactions. It is classified as an allyl ester and contains a bromo and a methyl group attached to the propionate functional group. ALLYL 2-BROMO-2-METHYLPROPIONATE is utilized in the production of pharmaceuticals, agrochemicals, and other industrial chemicals. It is important to handle this chemical with caution as it is flammable and may cause irritation to the skin, eyes, and respiratory system upon exposure. Additionally,

InChI:InChI=1/C7H11BrO2/c1-4-5-10-6(9)7(2,3)8/h4H,1,5H2,2-3H3

Upstream product

• 107-18-6 allyl alcohol 
• 75-98-9 Trimethylacetic acid 
• 15727-77-2 Prop-2-enyl 2-methylpropionate 
• 20769-85-1 2-bromoisobutyric acid bromide 

Downstream Products

• 892860-15-0 2-{10-[4-(benzyloxycarbonyl-methyl-amino)-3-benzyloxycarbonyloxy-6-methyl-tetrahydro-pyran-2-yloxy]-2-ethyl-3,4-dihydroxy-9-methoxy-3,5,7,9,11,13-hexamethyl-12,14-dioxo-oxacyclotetradec-6-ylideneaminooxy}-2-methyl-propionic acid allyl ester 
• 370870-81-8 3-(chlorodimethylsilyl)propyl 2-bromo-2-methylpropanoate 
• 880339-31-1 {[(2-bromo-2-methylpropionyl)oxy]propyl}triethoxysilane 
• 892860-19-4 C₅₃H₇₂N₂O₁₇ 
• 265119-86-6 2-bromo-2-methyl-propionic acid 3-(ethoxy-dimethyl-silanyl)-propyl ester 
• 314021-97-1 (3-trimethoxysilyl)-propyl 2-bromo-2-methylpropionate 

Relevant articles and documents

Copper(I) mediated radical polymerisation of uridine and adenosine monomers on a silica support

Copper(I) mediated radical polymerisation is used to polymerise uridine and adenosine substituted methacrylates onto a silica surface giving supported polymers with potential as re-usable templates and for interaction with nucleic acids.

Mechanically reinforced silica aerogel nanocomposites via surface initiated atom transfer radical polymerizations

Here we report the preparation of mechanically robust silica aerogel polymer nanocomposites using surface-initiated atom transfer radical polymerization. This approach was used to grow poly(methyl methacrylate) (PMMA) with low polydispersities and establish the first structure-property relationship between the grafted PMMA molecular weight and bulk physical properties of the hybrid aerogel.

Mannosylated Poly(ethylene imine) Copolymers Enhance saRNA Uptake and Expression in Human Skin Explants

Messenger RNA (mRNA) is a promising platform for both vaccines and therapeutics, and self-amplifying RNA (saRNA) is particularly advantageous, as it enables higher protein expression and dose minimization. Here, we present a delivery platform for targeted delivery of saRNA using mannosylated poly(ethylene imine) (PEI) enabled by the host-guest interaction between cyclodextrin and adamantane. We show that the host-guest complexation does not interfere with the electrostatic interaction with saRNA and observed that increasing the degree of mannosylation inhibited transfection efficiency in vitro, but enhanced the number of cells expressing GFP by 8-fold in human skin explants. Besides, increasing the ratio of glycopolymer to saRNA also enhanced the percentage of transfected cells ex vivo. We identified that these mannosylated PEIs specifically increased protein expression in the epithelial cells resident in human skin in a mannose-dependent manner. This platform is promising for further study of glycosylation of PEI and targeted saRNA delivery.

Liquid crystal mono- and nano-layers covalently bonded to silicon and silica surface for alignment of LC layers

We synthesized two types of liquid crystalline nano-layers covalently bonded to Si and Si/SiO2 wafers. Monolayers of terminal and lateral low molecular weight mesogens exhibit spontaneous homeotropic orientation, while planar orientation is obtained by means of rubbing process. On the other hand a novel polymer liquid crystal nano-layer, obtained via atom transfer radical polymerization (ATRP) of acrylate monomer from Si/SiO2 surface, exhibits planar orientation of liquid crystalline side chain moieties. Structure of such novel composites was confirmed by optical studies as well as spectroscopic methods, including ellipsometry. The goal was to obtain low molecular weight liquid crystals alignment just from the mentioned above, modified surfaces. Copyright Taylor & Francis Group, LLC.