40636-99-5

Basic information

• Product Name: 2(5H)-Furanone, 4-chloro-5-hydroxy-
• CAS NO: 40636-99-5
• Molecular Formula: C4H3ClO3
• Molecular Weight: 134.519
• Mol File: 40636-99-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2(5H)-Furanone, 4-chloro-5-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(5H)-Furanone, 4-chloro-5-hydroxy-(40636-99-5)
• EPA Substance Registry System: 2(5H)-Furanone, 4-chloro-5-hydroxy-(40636-99-5)

Safety Data

• Hazardous Substances Data: 40636-99-5(Hazardous Substances Data)

Usage

Natural occurrence

Found in various fruits and vegetables (e.g. strawberries, pineapples, tomatoes)

Responsible for

Characteristic sweet, caramel-like aroma in fruits and vegetables

Usage

Flavor and fragrance agent in the food and beverage industry, production of flavoring agents, chemical intermediate in the synthesis of pharmaceuticals and other organic compounds

Health benefits

Potential antioxidant and anti-inflammatory properties

Adverse effects

Excessive consumption or exposure to high levels may have potential adverse effects on health

Upstream product

• 107-20-0 2-chloroethanal 
• 298-12-4 Glyoxilic acid 
• 563-96-2 2,2-dihydroxyacetic acid 
• 98-01-1 furfural 

Downstream Products

• 14628-34-3 5-chloro-2-methyl-3(2H)-pyridazinone 
• 766-40-5 Mucochloric acid 

Relevant articles and documents

Synthesis of functionalized pyridazin-3(2 H)-ones via nucleophilic substitution of hydrogen (SNH)

Reaction of 2-benzyl-5-halopyridazin-3(2H)-ones (3) with Grignard reagents followed by quenching with electrophiles unexpectedly yielded 4,5-disubstituted pyridazin-3(2H)-ones instead of 5-substituted pyridazin-3(2H)-ones. These reactions represent the fi

Synthesis and characterization of both enantiomers of trans-1,2-di-(2-hydroxy-2-propyl)-cyclobutane

Both enantiomers of the title compound are synthesized for the first time in four steps including a [2+2]-photocycloaddition to build up the cyclobutane backbone and a cerium supported reductive permethylation. During the cerium supported process a complete and selective change in the configuration of the cyclobutane ring takes place. The substituents are transformed from the cis- to the trans-geometry.