40637-56-7 Usage
Description
Dimethyl allylmalonate is an organic compound that serves as a crucial intermediate in various chemical syntheses. It is characterized by its unique chemical structure, which allows it to participate in a wide range of reactions and contribute to the formation of diverse products.
Uses
Used in Organic Synthesis:
Dimethyl allylmalonate is used as a key intermediate in organic synthesis for the production of various compounds. Its versatile structure enables it to be a valuable building block in the creation of complex organic molecules.
Used in Pharmaceuticals:
In the pharmaceutical industry, dimethyl allylmalonate is utilized as a vital raw material for the synthesis of different medicinal compounds. Its reactivity and compatibility with various functional groups make it an essential component in the development of new drugs.
Used in Agrochemicals:
Dimethyl allylmalonate also finds application in the agrochemical sector, where it is employed as a starting material for the synthesis of various agrochemical products. Its role in this industry is crucial for the development of effective and environmentally friendly solutions for agricultural needs.
Used in Dyestuffs:
In the dyestuffs industry, dimethyl allylmalonate is used as an important intermediate for the production of a range of dyes and pigments. Its ability to form diverse chemical structures allows for the creation of a wide variety of colorants used in various applications, such as textiles, plastics, and printing inks.
Synthesis Reference(s)
Journal of the American Chemical Society, 105, p. 7757, 1983 DOI: 10.1021/ja00364a055Tetrahedron Letters, 23, p. 5549, 1982 DOI: 10.1016/S0040-4039(00)85891-8
Check Digit Verification of cas no
The CAS Registry Mumber 40637-56-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,6,3 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 40637-56:
(7*4)+(6*0)+(5*6)+(4*3)+(3*7)+(2*5)+(1*6)=107
107 % 10 = 7
So 40637-56-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H12O4/c1-4-5-6(7(9)11-2)8(10)12-3/h4,6H,1,5H2,2-3H3
40637-56-7Relevant articles and documents
Palladium-catalyzed intra-molecular olefin insertion reaction of α-alkenyl-α-acyloxytrialkylsilane. Synthesis of optically active carbocycle
Sakaguchi, Kazuhiko,Okada, Takuya,Yamada, Takeshi,Ohfune, Yasufumi
, p. 3925 - 3928 (2007)
Pd-catalyzed intra-molecular olefin insertion/carbonylation reaction of optically active α-alkenyl-α-acyloxysilanes is described. The reactions proceeded in a stereoselective manner to give five- and six-membered optically active carbocycles having (E)-vinylsilane in their side chains. Under CO condition, optically active carbocycles containing one-carbon homologated side chain were produced by Pd-catalyzed tandem olefin insertion-carbonylation reaction.
Metal-Free Domino Oligocyclization Reactions of Enynals and Enynones with Molecular Oxygen
Abbasi Kejani, Alireza,Khosravi, Hormoz,Rominger, Frank,Balalaie, Saeed,Breit, Bernhard
supporting information, p. 1291 - 1295 (2021/02/20)
A novel metal-free direct addition of molecular oxygen to the C-C triple bond toward benzannulated oxygen-bridged seven-membered ring systems and aza[3.1.0]bicycle skeletons under 3O2 atmosphere has been described. The reaction proceeds through at least three intramolecular C-O and C-C bond forming steps via green, simple, and unprecedented domino radical processes with high selectivity and good yields.
Enantioselective α-Amination of Acyclic 1,3-Dicarbonyls Catalyzed by N-Heterocyclic Carbene
Santra, Surojit,Maji, Ujjwal,Guin, Joyram
supporting information, p. 468 - 473 (2020/02/04)
Herein, we describe a method for the catalytic enantioselective α-amination of α-substituted acyclic 1,3-ketoamides and 1,3-amidoesters that affords the products possessing N-substituted quaternary stereocenters with a chiral N-heterocyclic carbene (NHC). The reaction is based on the utilization of an intrinsic Br?nsted base characteristic of NHC that enables the catalytic formation of a chiral ion pair comprising the enolate and the azolium ion. A series of challenging open-chain α-substituted 1,3-dicarbonyls are aminated via this method with ee's of ≤99%.
