406476-31-1

Basic information

• Product Name: 5'-TRIFLUOROMETHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-4-CARBOXYLIC ACID
• Synonyms: TIMTEC-BB SBB010208;5'-TRIFLUOROMETHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-4-CARBOXYLIC ACID;AKOS BBS-00001580;AKOS B034494;1-[5-(TRIFLUOROMETHYL)-2-PYRIDYL]PIPERIDINE-4-CARBOXYLIC ACID;1-[5-(TRIFLUOROMETHYL)PYRID-2-YL]PIPERIDINE-4-CARBOXYLIC ACID;1-[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]PIPERIDINE-4-CARBOXYLIC ACID;BUTTPARK 30\03-94
• CAS NO: 406476-31-1
• Molecular Formula: C₁₂H₁₃F₃N₂O₂
• Molecular Weight: 274.24
• Product Categories: Carboxylic Acids;Pyrans, Piperidines &Piperazines;Carboxylic Acids;Pyrans, Piperidines & Piperazines
• Mol File: 406476-31-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 162 °C
• Boiling Point: 420.1 °C at 760 mmHg
• Flash Point: 207.9 °C
• Appearance: off-white solid.
• Density: 1.366 g/cm³
• Vapor Pressure: 8.29E-08mmHg at 25°C
• Refractive Index: 1.512
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 5'-TRIFLUOROMETHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-TRIFLUOROMETHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-4-CARBOXYLIC ACID(406476-31-1)
• EPA Substance Registry System: 5'-TRIFLUOROMETHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-4-CARBOXYLIC ACID(406476-31-1)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45
• HazardClass: IRRITANT
• Hazardous Substances Data: 406476-31-1(Hazardous Substances Data)

Usage

General Description

5'-TRIFLUOROMETHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-4-CARBOXYLIC ACID is a chemical compound with the molecular formula C15H13F3N2O2. It is a derivative of the bipyridine family and contains both a carboxylic acid functional group and a trifluoromethyl group. 5'-TRIFLUOROMETHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-4-CARBOXYLIC ACID has potential applications in medicinal chemistry, particularly in the development of pharmaceutical drugs. Its unique structure and functional groups make it a target for research into its potential biological and pharmacological activities. The trifluoromethyl group can also enhance the compound's properties, such as lipophilicity and metabolic stability, making it a valuable tool in drug discovery and development.

InChI:InChI=1/C12H13F3N2O2/c13-12(14,15)9-1-2-10(16-7-9)17-5-3-8(4-6-17)11(18)19/h1-2,7-8H,3-6H2,(H,18,19)

Upstream product

• 420844-59-3 ethyl 1-[5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylate 

Relevant articles and documents

1, 4-DISUBSTITUTED PIPERIDINES AS VASOPRESSIN RECEPTOR VIA ANTAGONISTS

The present invention provides compounds of formula (1) compositions comprising such compounds; the use of such compounds in therapy (such as in the treatment of dysmenorrhoea); and methods of treating patients with such compounds; wherein A and G are as defined herein.

PIPERIDINE/CYCLOHEXANE CARBOXAMIDE DERIVATIVES FOR USE AS VANILLOID RECEPTOR MODULATORS

Certain compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, P, P', X, m and n are as defined in the specification, a process for preparing such compounds, a pharmaceutical composition c