40663-79-4

Basic information

• Product Name: 4-methyl-4-p-tolyl-valeric acid
• Synonyms: 4-methyl-4-p-tolyl-valeric acid
• CAS NO: 40663-79-4
• Molecular Weight: 206.285
• Mol File: 40663-79-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-methyl-4-p-tolyl-valeric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-4-p-tolyl-valeric acid(40663-79-4)
• EPA Substance Registry System: 4-methyl-4-p-tolyl-valeric acid(40663-79-4)

Safety Data

• Hazardous Substances Data: 40663-79-4(Hazardous Substances Data)

Upstream product

• 4619-20-9 3-(4-methylbenzoyl)propionic acid 
• 108-88-3 toluene 
• 4786-23-6 4-methyl-3-pentenenitrile 
• 64854-53-1 4-methyl-4-(4-methylphenyl)pentanenitrile 
• 6942-61-6 ethyl 4-oxo-4-(p-tolyl)butanoate 
• 75-24-1 trimethylaluminum 
• 21034-34-4 (±)-5-(4-methylphenyl)-γ-valerolactone 

Downstream Products

• 158574-91-5 3-Ethyl-6-methyl-6-p-tolyl-heptan-3-ol 
• 64854-55-3 4-methyl-4(4-methyl-1,4-cyclohexadien-1-yl)pentanoic acid 
• 64854-56-4 4-methyl-4(4-methyl-1,3-cyclohexadien-1-yl)pentanoic acid 
• 30364-38-6 1,2-dihydro-1,1,6-trimethyl-naphthalene 
• 591254-62-5 2-(benzhydrylidene-amino)-3-(5,5-dimethyl-8-oxo-5,8-dihydro-naphthalen-2-yl)-propionic acid methyl ester 
• 70358-65-5 4,4,7-trimethyl-3,4-dihydronaphthalen-1(2H)-one 
• 158574-90-4 ethyl 4-methyl-4-(4-methylphenyl)pentanoate 

Relevant articles and documents

Synthesis of Deuterium-Labeled 1,1,6-Trimethyl-1,2-dihydronaphthalene (TDN) and Quantitative Determination of TDN and Isomeric Vitispiranes in Riesling Wines by a Stable-Isotope-Dilution Assay

The C13-norisoprenoid aroma compounds 1,1,6-trimethyl-1,2-dihydronaphthalene (TDN) and isomeric 2,10,10-trimethyl-6-methylene-1-oxaspiro[4.5]dec-7-enes, so-called vitispiranes, are considered to be biosynthetically related. They occur at higher concentrations in bottle-aged Riesling wines especially and are important contributors to the varietal aroma of Riesling wines. Because of the variation of the quantitative methods and data reported in the literature, a redetermination of concentration levels for both free and total TDN and isomeric vitispiranes, especially in German Riesling wines, was performed using a stable-isotope-dilution assay (SIDA). For this purpose, a novel six-step synthetic route to TDN and deuterium-labeled TDN was developed. A standardized sample preparation for TDN and vitispiranes and a rapid acid-hydrolysis method at genuine wine-pH conditions for the conversion of the precursors into TDN and vitispiranes were also developed. Automated HS-SPME was applied to 250 wine samples from two wine competitions, and analysis was performed by gas chromatography-mass spectrometry with selected-ion monitoring (GC-SIM-MS) as well as selected-reaction monitoring (GC-SRM-MS).

Novel process for the synthesis of tricyclo[6.2.2.03,8 ]dodecane derivatives

A novel process for the preparation of tricyclo[6.2.2.03,8 ]dodecane derivatives is presented. This novel process is applied to the synthesis of the odorant 4-acetyl-1,7,7-trimethyltricyclo[6.2.2.03,8 ]-3-dodecene, also known as 4-ac