40670-79-9

Basic information

• Product Name: 1,3-thiazolidine-4-thione
• CAS NO: 40670-79-9
• Molecular Formula: C₃H₅NS₂
• Molecular Weight: 119.2085
• Mol File: 40670-79-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 217.2°C at 760 mmHg
• Flash Point: 85.2°C
• Density: 1.38g/cm³
• Vapor Pressure: 0.134mmHg at 25°C
• Refractive Index: 1.681
• CAS DataBase Reference: 1,3-thiazolidine-4-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-thiazolidine-4-thione(40670-79-9)
• EPA Substance Registry System: 1,3-thiazolidine-4-thione(40670-79-9)

Safety Data

• Hazardous Substances Data: 40670-79-9(Hazardous Substances Data)

Upstream product

• 2281-74-5 4-oxothiazolidine 

Relevant articles and documents

Bicyclic 6-alkylidene-penems as class-D beta-lactamases inhibitors

This invention relates to certain bicyclic 6-alkylidene penems which act as a inhibitor of class-D enzymes. β-Lactamases hydrolyze β-lactam antibiotics, and as such serve as the primary cause of bacterial resistance. The compounds of the present invention when combined with β-lactam antibiotics will provide an effective treatment against life threatening bacterial infections. In accordance with the present invention there are provided compounds of general formula I or a pharmaceutically acceptable salt or in vivo hydrolyzable ester R5 thereof: wherein: One of A and B denotes hydrogen and the other an optionally substituted fused bicyclic heteroaryl group; and X═O or S.

BICYCLIC 6-ALKYLIDENE-PENEMS AS ?-LACTAMASES INHIBITORS

The present invention provides a compound of Formula (I), pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof.