40731-16-6 Usage
General Description
5-CHLORO-3-METHYL-1H-INDOLE-2-CARBALDEHYDE is a chemical compound with the molecular formula C10H8ClNO. It is a derivative of indole, which is a heterocyclic aromatic organic compound. This chemical is an aldehyde, meaning it contains a carbonyl group (C=O) bonded to a hydrogen atom and an R group. The 5-chloro and 3-methyl substituents on the indole ring are responsible for its specific chemical properties and reactivity. It is commonly used as an intermediate or building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 40731-16-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,7,3 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 40731-16:
(7*4)+(6*0)+(5*7)+(4*3)+(3*1)+(2*1)+(1*6)=86
86 % 10 = 6
So 40731-16-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H8ClNO/c1-6-8-4-7(11)2-3-9(8)12-10(6)5-13/h2-5,12H,1H3
40731-16-6Relevant articles and documents
En Route to 2-(Cyclobuten-1-yl)-3-(trifluoromethyl)-1H-indole
Gazvoda, Martin,Krivec, Marko,?asar, Zdenko,Ko?mrlj, Janez
, p. 2486 - 2493 (2018/02/23)
A six-step synthetic route from 4-chloro-2-methylaniline to 5-chloro-2-(cyclobut-1-en-1-yl)-3-(trifluoromethyl)-1H-indole (1) has been reported. Compound 1a is a key impurity of reverse transcriptase inhibitor efavirenz, an important anti-HIV/AIDS drug. Synthetic challenges, dead ends, and detours are discussed.
The synthesis and transformations of some 3 chloro and 3 nitroindolenines
Walser,Blount,Fryer
, p. 3077 - 3084 (2007/10/07)
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