40740-41-8

Basic information

• Product Name: 4-IODOPYRROLE-2-CARBOXYLIC ACID METHYL ESTER
• Synonyms: 4-IODOPYRROLE-2-CARBOXYLIC ACID METHYL ESTER;methyl 4-iodo-1H-pyrrole-2-carboxylate;Methyl 4-iodo-2-pyrrolecarboxylate;Methyl 4-iodopyrrole-2-carboxylate, 97%;1H-Pyrrole-2-carboxylic acid, 4-iodo-, methyl ester
• CAS NO: 40740-41-8
• Molecular Formula: C₆H₆INO₂
• Molecular Weight: 251.02
• Mol File: 40740-41-8.mol
• Article Data: 11

Chemical Properties

• Melting Point: 77-78°
• Boiling Point: 334.292 °C at 760 mmHg
• Flash Point: 155.975 °C
• Appearance: White to brown/Solid
• Density: 1.965 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.629
• Storage Temp.: 2-8°C(protect from light)
• Sensitive: Light Sensitive
• CAS DataBase Reference: 4-IODOPYRROLE-2-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-IODOPYRROLE-2-CARBOXYLIC ACID METHYL ESTER(40740-41-8)
• EPA Substance Registry System: 4-IODOPYRROLE-2-CARBOXYLIC ACID METHYL ESTER(40740-41-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 40740-41-8(Hazardous Substances Data)

Usage

General Description

4-Iodopyrrole-2-carboxylic acid methyl ester is a chemical compound with the molecular formula C7H6INO2. It is an ester derivative of 4-iodopyrrole-2-carboxylic acid, which is a heterocyclic compound containing both iodine and carboxylic acid functional groups. 4-Iodopyrrole-2-carboxylic acid methyl ester is commonly used in organic synthesis and medicinal chemistry, as it can serve as a precursor for the synthesis of various biologically active molecules. It is also a valuable building block for the preparation of pharmaceuticals and agrochemicals. Due to its potential applications in drug discovery and development, 4-iodopyrrole-2-carboxylic acid methyl ester is a widely studied compound in the field of chemical research and drug design.

InChI:InChI=1/C6H6INO2/c1-10-6(9)5-2-4(7)3-8-5/h2-3,8H,1H3

Upstream product

• 67-56-1 methanol 
• 72652-33-6 4-iodo-2-(trichloroacetyl)pyrrole 
• 124-41-4 sodium methylate 
• 1193-62-0 methyl Pyrrole-2-carboxylate 
• 35302-72-8 pyrrol-2-yl trichloromethyl ketone 

Downstream Products

• 40740-42-9 4-iodo-1-methyl-pyrrole-2-carboxylic acid methyl ester 
• 1973505-15-5 t-butyl 7-iodo-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate 
• 869886-88-4 4-(5-chloro-2-isopropylaminopyridin-4-yl)-1-(toluene-4-sulfonyl)-1H-pyrrole-2-carboxylic acid methyl ester 
• 869886-86-2 methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxoborolan-2-yl)-1-p-toluenesulfonyl-1H-pyrrole-2-carboxylate 
• 869886-67-9 4-[5-chloro-2-[(1-methylethyl)amino]-4-pyridinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide 
• 869886-90-8 4-(5-chloro-2-isopropylaminopyridin-4-yl)-1H pyrrole-2-carboxylic acid 
• 90433-90-2 methyl 4-(prop-1-en-2-yl)-1H-pyrrole-2-carboxylate 
• 869886-85-1 4-iodo-1-(toluene-4-sulfonyl)-1H-pyrrole-2-carboxylic acid methyl ester 
• 194796-32-2 C₁₇H₁₂Cl₂N₂O₄ 
• 903560-42-9 methyl 4-phenyl-1H-pyrrole-2-carboxylate 
• 903560-51-0 methyl 5-chloro-4-iodo-1H-pyrrole-2-carboxylate 
• 2436-96-6 1-nitro-2-(2-nitrophenyl)benzene 
• 52635-93-5 methyl 4-(2-nitrophenyl)-1H-pyrrole-2-carboxylate 
• 194796-31-1 C₁₉H₁₄Cl₂I₂N₂O₄ 

Relevant articles and documents

RESORCINOL DERIVATIVE AS HSP90 INHIBITOR

The present invention relates to a compound represented by formula (I) of a resorcinol derivative as an HSP90 inhibitor or pharmaceutically accepted salts thereof. The compound in the present invention has the activity of inhibiting heat shock protein HSP90. Therefore, the compound in the present invention is used to treat proliferative diseases such as cancer and neurodegenerative diseases. The present invention further provides the compounds and preparation methods for pharmaceutical compositions comprising the compounds, a method for treating diseases, and pharmaceutical compositions comprising the compounds.

Highly Regioselective Iodination of Arenes via Iron(III)-Catalyzed Activation of N-Iodosuccinimide

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BICYCLO-SUBSTITUTED PYRAZOLON AZO DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF

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