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40810-36-4

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40810-36-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 40810-36-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,8,1 and 0 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 40810-36:
(7*4)+(6*0)+(5*8)+(4*1)+(3*0)+(2*3)+(1*6)=84
84 % 10 = 4
So 40810-36-4 is a valid CAS Registry Number.

40810-36-4Downstream Products

40810-36-4Relevant articles and documents

Mechanism-Based Design of an Amide-Directed Ni-Catalyzed Arylboration of Cyclopentene Derivatives

Lambright, Alison L.,Liu, Yanyao,Joyner, Isaac A.,Logan, Kaitlyn M.,Brown, M. Kevin

supporting information, p. 612 - 616 (2021/01/26)

A method for amide-directed Ni-catalyzed diastereoselective arylboration of cyclopentenes is disclosed. The reaction allows for the synthesis of sterically congested cyclopentane scaffolds that contain an easily derivatized boronic ester and amide functional handles. The nature of the amide directing group and its influence on the reaction outcome are investigated and ultimately reflect a predictably selective reaction based on the solvent and base counterion.

New derivatives of benzylamide with anticonvulsant activity

Strupinska, Marzanna,Rostafinska-Suchar, Grazyna,Stables, James. P.,Paruszewski, Ryszard

experimental part, p. 155 - 159 (2009/06/18)

Previously obtained picolinic acid benzylamide is a potent anticonvulsant with low neurotoxicity. In search for new effective anticonvulsants twelve new benzylamides (1-12) were synthesized and preliminary evaluated in the Anticonvulsant Screening Program (ASP) of Antiepileptic Drug Development Program (ADDP) of NIH. Two of them appeared the most promising: 1- cyclopentenecarboxylic acid benzylamide (1- Cpc-BZA) (9) showed MES ED 50 = 85,36 mg/kg (PI = 2,49), scPTZ ED50 = 1,37 mg/kg (PI = 1,37), 6Hz-EST ED50 = 50,29 mg/kg and cyclopentanecarboxylic acid benzylamide (Cpc-BZA) (11) showed pilocarpine ED50 = 154.75 mg/kg and pilocarpine ED97 = 270.95 mg/kg.

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