40829-04-7

Basic information

• Product Name: D-Tyrosinol hydrochloride
• Synonyms: L-TYROSINOL HCL;D-TYROSINOL HCL;D-TYROSINOL HYDROCHLORIDE;H-D-TYR-OL HCL;H-TYR-OL HCL;H-L-TYR-OL HCL;(R)-3-(4-HYDROXYPHENYL)-2-AMINO-1-PROPANOL HCL;(R)-BETA-AMINO-4-HYDROXYBENZENEPROPANOL HYDROCHLORIDE
• CAS NO: 40829-04-7
• Molecular Formula: C9H14ClNO2
• Molecular Weight: 203.67
• Product Categories: Amino Acid Derivatives;Amino Alcohols;Peptide Synthesis
• Mol File: 40829-04-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 167 °C
• Boiling Point: 398.8 °C at 760 mmHg
• Flash Point: 195 °C
• Appearance: white to off-white granular powder
• Storage Temp.: 0-6°C
• CAS DataBase Reference: D-Tyrosinol hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: D-Tyrosinol hydrochloride(40829-04-7)
• EPA Substance Registry System: D-Tyrosinol hydrochloride(40829-04-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• Hazardous Substances Data: 40829-04-7(Hazardous Substances Data)

Usage

Description

D-Tyrosinol hydrochloride is a chemical compound derived from the amino acid tyrosine, featuring a hydroxyl group attached to the aromatic ring. It is a chiral molecule with the D-configuration, which means it has a specific three-dimensional arrangement of atoms. D-Tyrosinol hydrochloride is soluble in water and is commonly used in various chemical and pharmaceutical applications due to its unique properties.

Uses

Used in Organic Synthesis:
D-Tyrosinol hydrochloride is used as a reagent and reactant in organic synthesis for the preparation of various organic compounds. Its hydroxyl group allows for a range of chemical reactions, such as esterification, etherification, and condensation, making it a versatile building block for the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, D-Tyrosinol hydrochloride is used as an intermediate in the synthesis of drugs and active pharmaceutical ingredients (APIs). Its chiral nature and reactivity make it a valuable component in the development of enantiomerically pure compounds, which are essential for the production of many medications.
Used in Analytical Chemistry:
D-Tyrosinol hydrochloride can also be employed as a chiral reference standard in analytical chemistry. It is used to calibrate instruments and establish methods for the separation and identification of enantiomers, which is crucial for ensuring the purity and efficacy of chiral drugs.
Used in Research and Development:
In research and development settings, D-Tyrosinol hydrochloride serves as a valuable tool for studying the properties and behavior of chiral compounds. It can be used to investigate the stereochemistry of reactions, explore the binding of molecules to biological targets, and develop new methods for the synthesis of enantiomerically pure compounds.
Overall, D-Tyrosinol hydrochloride is a multifaceted compound with applications spanning across various industries, including organic synthesis, pharmaceuticals, analytical chemistry, and research and development. Its unique properties and reactivity make it an indispensable component in the development and production of a wide range of products.

InChI:InChI=1/C9H13NO2.ClH/c10-8(6-11)5-7-1-3-9(12)4-2-7;/h1-4,8,11-12H,5-6,10H2;1H/t8-;/m1./s1

Upstream product

• 102440-13-1 (+/-)-2-amino-3-(4-hydroxy-phenyl)-propan-1-ol; hydrochloride 
• 60-18-4 L-tyrosine 
• 3417-91-2 L-tyrosine methyl ester HCl 

Downstream Products

• 87579-21-3 C₁₈H₂₁NO₃ 
• 1290036-10-0 C₂₀H₂₅NO₄ 
• 1290036-03-1 (S)-O-benzyl tyrosinol 
• 1513888-59-9 (R)-N-(1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl)propionamide 
• 1513888-75-9 (9Z,12Z,15Z)-N-((2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl)octadeca-9,12,15-trienamide 
• 1513888-74-8 (9Z,12Z)-N-((2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl)octadeca-9,12-dienamide 
• 1513888-73-7 (S)-15-hydroxy-N-(1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl)pentadecanamide 
• 1513888-72-6 (S)-N-(1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl)palmitamide 
• 1513888-68-0 (S)-4-(2-(hexadecylamino)-3-hydroxypropyl)phenol 
• 1513888-71-5 4-((2S)-3-hydroxy-2-((9Z,12Z,15Z)-octadeca-9,12,15-trien-1-ylamino)propyl)phenol 
• 1513888-70-4 4-((2S)-3-hydroxy-2-((9Z,12Z)-octadeca-9,12-dien-1-ylamino)propyl)phenol 
• 1513888-63-5 (S)-4-(1-(adamantan-1-yl)-1H-1,2,3-triazol-4-yl)-N-(1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl)butanamide 
• 1513888-78-2 (S)-N-(1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl)hex-5-ynamide 

Relevant articles and documents

Heterogeneous Catalytic Hydrogenation of Chiral Amino Acid Methyl Esters to Amino Alcohols with Retention of Configuration Over Mg-Modified Cu/ZnO/Al2O3 Catalyst

Selective hydrogenation of amino acid methyl esters to chiral amino alcohols is an important and fascinating process. The CuZn0.3Mg0.1AlOx catalyst for the synthesis of chiral amino alcohols was prepared by the fractional

Synthesis of lipoamino acids and their activity against cerebral ischemic injury

A series of lipoamino acids were synthesized and their neuroprotective effect against brain ischemia induced by oxygen-glucose deprivation (OGD) on rat cerebral slices was evaluated. Among these compounds, N-stearoyl-L-tyrosine (4), N-stearoyl-L-serine (5) and N-stearoyl-L-threonine (6) exhibited good neuroprotective activity. We found that the neuroprotective activity of lipoamino acids depended on the acyl group, the presence of a free carboxylic function and a free hydroxyl group at the branched chain of the amino acids. The results also showed that 5 was the most active compound, protecting rat brain slices against OGD as well as hydrogen peroxide (H2O2) insult at the range of 1-10 M.