40843-54-7

Basic information

• Product Name: 4-(4-methoxyphenoxy)biphenyl
• CAS NO: 40843-54-7
• Molecular Formula: C₁₉H₁₆O₂
• Molecular Weight: 276.3291
• Mol File: 40843-54-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 410.5°C at 760 mmHg
• Flash Point: 161.3°C
• Density: 1.108g/cm³
• Vapor Pressure: 1.42E-06mmHg at 25°C
• Refractive Index: 1.588
• CAS DataBase Reference: 4-(4-methoxyphenoxy)biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-methoxyphenoxy)biphenyl(40843-54-7)
• EPA Substance Registry System: 4-(4-methoxyphenoxy)biphenyl(40843-54-7)

Safety Data

• Hazardous Substances Data: 40843-54-7(Hazardous Substances Data)

Upstream product

• 100-17-4 para-methoxynitrobenzene 
• 92-69-3 4-Phenylphenol 
• 696-62-8 para-iodoanisole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 150-76-5 4-methoxy-phenol 

Downstream Products

• 40843-33-2 2-[4-(Biphenyl-4-yloxy)-phenoxy]-propionic acid 
• 40843-39-8 [4-(Biphenyl-4-yloxy)-phenoxy]-phenyl-acetic acid 
• 40843-55-8 4-([1,1'-biphenyl]-4-yloxy)phenol 

Relevant articles and documents

Pd-Catalyzed Etherification of Nitroarenes

The Pd-catalyzed etherification of nitroarenes with arenols has been achieved using a new rationally designed ligand. Mechanistic insights were used to design the ligand so that both the oxidative addition and reductive elimination steps of a plausible catalytic cycle were facilitated. The catalytic system established here provides direct access to a range of unsymmetrical diaryl ethers from nitroarenes.

Diaryl Ether Formation Merging Photoredox and Nickel Catalysis

Photoredox and Ni catalysis are combined to produce diaryl ethers under mild conditions. A broad range of aryl halides and phenol derivatives are cross-coupled in the presence of a readily available organic photocatalyst and NiBr2(dtbpy). Symmetrical diaryl ethers have also been directly obtained from aryl bromides in the presence of water. Mechanistic investigations support the involvement of Ni(0) species at the outset of the reaction and a Ni(II)/Ni(III)-photocatalyzed single electron transfer process preceding the productive C(sp2)-OAr reductive elimination.

BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION

The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders. The compounds have general formula Ψ: An example is