408502-46-5

Basic information

• Product Name: 2,1,3-Benzoxadiazole-4-carboxamide(9CI)
• Synonyms: 2,1,3-Benzoxadiazole-4-carboxamide(9CI);Benzo[c][1,2,5]oxadiazole-4-carboxamide
• CAS NO: 408502-46-5
• Molecular Formula: C7H5N3O2
• Molecular Weight: 0
• Product Categories: AMIDE
• Mol File: 408502-46-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,1,3-Benzoxadiazole-4-carboxamide(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,1,3-Benzoxadiazole-4-carboxamide(9CI)(408502-46-5)
• EPA Substance Registry System: 2,1,3-Benzoxadiazole-4-carboxamide(9CI)(408502-46-5)

Safety Data

• Hazardous Substances Data: 408502-46-5(Hazardous Substances Data)

Usage

Class

Benzoxadiazole

Synthesis use

Fluorescent dyes, liquid crystals, and organic semiconductors

Optoelectronic potential

High photoluminescence quantum yield, good electron transporting properties

Antimicrobial activity

Exhibited by derivatives

Antitumor activity

Exhibited by derivatives

Antioxidant activity

Exhibited by derivatives

Applications

Pharmaceutical and materials science fields

Upstream product

• 111595-71-2 benzo[1,2,5]oxadiazole-4-carbonyl chloride 
• 32863-21-1 benzofurazan-4-carboxylic acid 
• 241818-86-0 4-benzofuroxancarbonitrile 
• 408502-47-6 benzofurazan-4-carboxylic acid methyl ester 

Relevant articles and documents

Nitroanilines are the reduction products of benzofuroxan system by oxyhemoglobin (HbO22+)

Benzofuroxans are interesting compounds which display several biochemical and pharmacological properties. Recent studies from our laboratory demonstrate that they are reduced by ferrous salts at room temperature and that the principal reaction products are o-nitroanilines. This paper shows that simple benzofuroxan derivatives are also able to oxidise HbO22+ to methemoglobin (MetHb3+) (UV detection) and to form o-nitroanilines (HPLC detection). From a toxicological point of view this reaction is interesting, since it indicates that the blood is a site for metabolism of these compounds with consequent methemoglobinemia and formation of toxic compounds.