4088-84-0

Basic information

• Product Name: 3-Cyano-4-fluorobenzotrifluoride
• Synonyms: 3-Cyano-4-fluorobenz;3-Cyano-4-fluorobenzotrifluoride, 3-Cyano-alpha,alpha,alpha,4-tetrafluorotoluene;2-FLUORO-5-(TRIFLUOROMETHYL)BENZONITRILE;3-CYANO-4-FLUOROBENZOTRIFLUORIDE;3-Cyano-4-fluorobenzotrifluoride~alpha,alpha,alpha,6-Tetrafluoro-m-tolunitrile;alpha,alpha,alpha-6-Tetrafluoro-m-tolunitrile;à,à,à,6-tetrafluoro-m-tolunitrile;2-Fluoro-5-(trifluoromethyl)benzonitrile 97%
• CAS NO: 4088-84-0
• Molecular Formula: C₈H₃F₄N
• Molecular Weight: 189.11
• Product Categories: Miscellaneous;Benzotrifluoride Series;Aromatic Nitriles
• Mol File: 4088-84-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 185-187°C
• Flash Point: 185-187°C
• Appearance: /
• Density: 1.373
• Vapor Pressure: 0.781mmHg at 25°C
• Refractive Index: 1.446
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• BRN: 2616671
• CAS DataBase Reference: 3-Cyano-4-fluorobenzotrifluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyano-4-fluorobenzotrifluoride(4088-84-0)
• EPA Substance Registry System: 3-Cyano-4-fluorobenzotrifluoride(4088-84-0)

Safety Data

• Hazard Codes: T,Xi,Xn
• Statements: 20/21/22-36/37/38-22
• Safety Statements: 26-36/37/39-45-36-36/37-23-9
• RIDADR: 3276
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 4088-84-0(Hazardous Substances Data)

Usage

General Description

3-Cyano-4-fluorobenzotrifluoride is a chemical compound with the molecular formula C8H3F4N. It is a colorless liquid with a molecular weight of 191.11 g/mol. 3-Cyano-4-fluorobenzotrifluoride is widely used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and materials. It is also used as an intermediate in the production of specialty chemicals. 3-Cyano-4-fluorobenzotrifluoride is known for its high reactivity and is often used in the pharmaceutical industry for the synthesis of various drug molecules. Additionally, it is also utilized in the production of pesticides and herbicides. Due to its versatile applications, 3-Cyano-4-fluorobenzotrifluoride is an important compound in the chemical industry.

InChI:InChI=1/C8H3F4N/c9-7-2-1-6(8(10,11)12)3-5(7)4-13/h1-3H

Downstream Products

• 660862-04-4 2-(4,5-difluoro-2-nitrophenylamino)-5-trifluoromethylbenzonitrile 
• 612506-48-6 2-(4-fluoro-2-nitrophenylamino)-5-trifluoromethylbenzonitrile 
• 2250-53-5 3-amino-5-(trifluoromethyl)-1H-indazole 
• 146137-78-2 2-fluoro-5-trifluoromethylbenzaldehyde 
• 133013-08-8 1-(2-Cyano-4-trifluoromethylphenyl)-4-pentafluroethylpyrimdin-6-one 
• 53984-37-5 2-(methylsulfanyl)-5-(trifluoromethyl)benzonitrile 
• 1196047-44-5 2-(5-chloro-1H-indol-1-yl)-5-(trifluoromethyl)benzonitrile 
• 1269407-48-8 1,1-dimethylethyl [(1S)-2-({(3S)-1-[2-cyano-4-(trifluoromethyl)phenyl]-3-pyrrolidinyl}amino)-2-oxo-1-(2-thienylmethyl)ethyl]carbamate 
• 1269407-91-1 1,1-dimethylethyl [(1S)-2-({(3S)-1-[2-cyano-4-(trifluoromethyl)phenyl]-3-pyrrolidin-yl}amino)-1-methyl-2-oxoethyl]carbamate-d1 
• 1269408-33-4 N₁-{(3S)-1-[2-cyano-4-(trifluoromethyl)phenyl]-3-pyrrolidinyl}-L-alaninamide hydrochloride 
• 1269408-34-5 (2S)-2-amino-N-{(3S)-1-[2-cyano-4-(trifluoromethyl)phenyl]-3-pyrrolidinyl}butanamide hydrochloride 
• 1269408-61-8 N₁-{(3S)-1-[2-cyano-4-(trifluoromethyl)phenyl]-3-pyrrolidinyl}-3-(2-thienyl)-L-alaninamide hydrochloride 
• 1269408-86-7 N₁-{(3S)-1-[2-cyano-4-(trifluoromethyl)phenyl]-3-pyrrolidinyl}-L-alaninamide-d1 hydrochloride 
• 1269408-85-6 N₁-{(3S)-1-[2-cyano-4-(trifluoromethyl)phenyl]-3-pyrrolidinyl}-L-alaninamide-d4 hydrochloride 

Relevant articles and documents

Process for producing trifluoromethylbenzylamines

The invention relates to a process for producing a trifluotomethylbenzylamine represented by the following general formula (1), 1where each R independently represents a halogen selected from the group consisting of fluorine, chlorine, bromine and iodine, an alkyl group having a carbon atom number of 1-4, an alkoxy group having a carbon atom number of 1-4, an amino group, a hydroxyl group or a trifluoromethyl group, and n represents an integer from 0 to 4. The process includes hydrogenating a trifluoromethylbenzonitrile by hydrogen in an organic solvent in the presence of ammonia and a catalyst containing a platinum group element. This trifluoromethylbenzonitrile is represented by the following general formula (2), 2where R and n are defined as above. With this process, it is possible to obtain the trifluoromethylbenzylamine at an extremely high yield.