40962-34-3

Basic information

• Product Name: (4-BROMOBENZYL)PHOSPHONIC ACID
• Synonyms: (4-BROMOBENZYL)PHOSPHONIC ACID;(4-Bromobenzyl)phosphonic acid, 98 %
• CAS NO: 40962-34-3
• Molecular Formula: C₇H₈BrO₃P
• Molecular Weight: 251.01
• Mol File: 40962-34-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4-BROMOBENZYL)PHOSPHONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (4-BROMOBENZYL)PHOSPHONIC ACID(40962-34-3)
• EPA Substance Registry System: (4-BROMOBENZYL)PHOSPHONIC ACID(40962-34-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 40962-34-3(Hazardous Substances Data)

Usage

Description

(4-BROMOBENZYL)PHOSPHONIC ACID is an organic compound that serves as a reagent in various chemical reactions and synthesis processes. It is characterized by the presence of a bromo group attached to a benzyl group, which is connected to a phosphonic acid moiety. This unique structure endows it with specific chemical properties that make it suitable for use in the synthesis of advanced materials.

Uses

Used in Semiconductor Industry:
(4-BROMOBENZYL)PHOSPHONIC ACID is used as a reagent for the synthesis of semiconducting conjugated polymer-nanowire nanocomposites. Its role in this application is crucial for creating materials with enhanced electrical and optical properties, which are essential for the development of advanced electronic devices and components.
In the synthesis process, (4-BROMOBENZYL)PHOSPHONIC ACID may act as a coupling agent, linking different components of the nanocomposites and facilitating the formation of a stable and functional material. The presence of the phosphonic acid group allows for strong interactions with metal or semiconductor surfaces, promoting the formation of a well-organized and highly conductive structure.
Furthermore, the use of (4-BROMOBENZYL)PHOSPHONIC ACID in the synthesis of semiconducting conjugated polymer-nanowire nanocomposites can lead to improved performance in various electronic applications, such as transistors, sensors, and photovoltaic devices. The resulting materials can exhibit enhanced charge transport, higher stability, and better compatibility with other components in electronic devices.

Upstream product

• 589-15-1 1-bromomethyl-4-bromobenzene 
• 38186-51-5 diethyl (4-bromobenzyl)phosphonate 

Downstream Products

• 98273-58-6 (4-Bromobenzyl)phosphonsaeure-dichloride 
• 38186-51-5 diethyl (4-bromobenzyl)phosphonate 

Relevant articles and documents

P Doped MoO3? x Nanosheets as Efficient and Stable Electrocatalysts for Hydrogen Evolution

A P doped MoO3? x nanocomposite material with rich oxygen vacancies is successfully fabricated by a two-step intercalation method, which presents superior activity for the hydrogen evolution reaction with low overpotential and fast electron transfer. In 0.5 m H2SO4, it displays an overpotential of 166 mV for driving the current density of 10 mA cm?2. Moreover, it also shows a good catalytic stability in the electrolytes with different pH, 0.5 m H2SO4 (strong acid), 0.5 m Na2SO4 (neutral solution), and 0.1 m NaOH (strong base). The superior catalytic activity and stability are due to to the synergistic effect between the P element doping and the oxygen vacancies.

Designing anti-inflammatory drugs from parasitic worms: A synthetic small molecule analogue of the acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis

In spite of increasing evidence that parasitic worms may protect humans from developing allergic and autoimmune diseases and the continuing identification of defined helminth-derived immunomodulatory molecules, to date no new anti-inflammatory drugs have been developed from these organisms. We have approached this matter in a novel manner by synthesizing a library of drug-like small molecules based upon phosphorylcholine, the active moiety of the anti-inflammatory Acanthocheilonema viteae product, ES-62, which as an immunogenic protein is unsuitable for use as a drug. Following preliminary in vitro screening for inhibitory effects on relevant macrophage cytokine responses, a sulfone-containing phosphorylcholine analogue (11a) was selected for testing in an in vivo model of inflammation, collagen-induced arthritis (CIA). Testing revealed that 11a was as effective as ES-62 in protecting DBA/1 mice from developing CIA and mirrored its mechanism of action in downregulating the TLR/IL-1R transducer, MyD88. 11a is thus a novel prototype for anti-inflammatory drug development.