41014-29-3

Basic information

• Product Name: 2,2'-Bibenzofuran
• Synonyms: 2,2'-bis(benzofuran);2-(benzofuran-2-yl)benzofuran;2,2'-bi(benzo[b]furan);di-2-benzo<2,3-b>furyl;2,2'-bi-1-benzofuran;[2,2']Bibenzofuranyl;2,2'-bibenzofuran
• CAS NO: 41014-29-3
• Molecular Formula: C16H10O2
• Molecular Weight: 234.254
• Mol File: 41014-29-3.mol
• Article Data: 9

Chemical Properties

• Melting Point: 197 °C
• Boiling Point: 384.6±17.0 °C(Predicted)
• Density: 1.242±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2,2'-Bibenzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-Bibenzofuran(41014-29-3)
• EPA Substance Registry System: 2,2'-Bibenzofuran(41014-29-3)

Safety Data

• Hazardous Substances Data: 41014-29-3(Hazardous Substances Data)

Usage

General Description

2,2'-Bibenzofuran is a chemical compound with the molecular formula C14H10O. It is a polycyclic aromatic hydrocarbon that contains two benzene rings fused together with a furan ring. It is commonly used in organic synthesis and as a precursor for the synthesis of other compounds. 2,2'-Bibenzofuran is also used as a building block in the production of dyes, pigments, pharmaceuticals, and herbicides. It has been studied for its potential biological and pharmacological activities, including its anticancer and antiviral properties. However, it is also known to be a potential environmental pollutant and is a subject of environmental concern due to its toxicity and persistence in the environment.

Upstream product

• 5101-44-0 2-ethynyl-phenol 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 402503-13-3 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]furan 
• 767-91-9 1-ethynyl-2-methoxybenzene 
• 73183-34-3 bis(pinacol)diborane 
• 271-89-6 1-benzofurane 
• 98437-24-2 benzofuran-2-boronic acid 
• 1679-18-1 4-Chlorophenylboronic acid 
• 496-16-2 2.3-dihydrobenzofuran 
• 558-37-2 tert-butylethylene 
• 184368-89-6 1-iodo-2-(tert-butyldimethylsilyloxy)benzene 
• 533-58-4 2-Iodophenol 
• 1431638-89-9 tert-butyldimethyl(2-((trimethylsilyl)ethynyl)phenoxy)silane 

Downstream Products

• 1198116-24-3 5',6'-diphenyl-2,2':3',2''-diepoxy-p-terphenyl 

Relevant articles and documents

Divergent Carbocatalytic Routes in Oxidative Coupling of Benzofused Heteroaryl Dimers: A Mechanistic Update

Mildly thermal air or HNO3 oxidized activated carbons catalyse oxidative dehydrogenative couplings of benzo[b]fused heteroaryl 2,2’-dimers, e.g., 2-(benzofuran-2-yl)-1H-indole, to chiral 3,3’-coupled cyclooctatetraenes or carbazole-type migrative products under O2 atmosphere. DFT calculations show that the radical cation and the Scholl-type arenium cation mechanisms lead to different products with 2-(benzofuran-2-yl)-1H-indole, being in accord with experimental product distributions.

An Active Palladium Colloidal Catalyst for the Selective Oxidative Heterocoupling of (Hetero)Aryl Boronic Acids

A highly selective oxidative heterocoupling protocol for (hetero)aryl boronic acids with an active palladium colloidal catalyst was developed. The judicious choice of electronically different aryl boronic acids made possible such couplings under mild conditions, with air as oxidant, while embracing a wide substrate scope. This successful approach further allowed the development of a unique one-pot sequential oxidative heterocoupling/Suzuki–Miyaura cross-coupling tandem process for accessing substituted terphenyls.

One-pot synthesis of 2,2′-bisbenzofurans using cuprous chloride as a catalyst

A variety of novel 5,5′-disubstituted-2,2′-bisbenzofuran derivatives were synthesized by treatment of 4-substituted-2-(2- trimethylsilylethynyl)phenyl tert-butyldimethylsilyl ether analogues with CuCl as a catalyst in 62-82% isolated yields. This novel st