4104-75-0

Basic information

• Product Name: N-METHYL-N-PHENYLTHIOUREA
• Synonyms: BUTTPARK 92\57-67;1-METHYL-1-PHENYL-2-THIOUREA;1-methyl-1-phenylthiourea;1-Phenyl-1-methylthiourea;1-Phenyl-1-methyl-thiourea
• CAS NO: 4104-75-0
• Molecular Formula: C₈H₁₀N₂S
• Molecular Weight: 166.24
• EINECS: 223-877-3
• Mol File: 4104-75-0.mol
• Article Data: 13

Chemical Properties

• Melting Point: 99 °C
• Boiling Point: 267.1 °C at 760 mmHg
• Flash Point: 115.3 °C
• Appearance: /
• Density: 1.221 g/cm³
• Vapor Pressure: 0.00831mmHg at 25°C
• Refractive Index: 1.679
• Water Solubility: Insoluble in water.
• CAS DataBase Reference: N-METHYL-N-PHENYLTHIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYL-N-PHENYLTHIOUREA(4104-75-0)
• EPA Substance Registry System: N-METHYL-N-PHENYLTHIOUREA(4104-75-0)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: UN2811
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 4104-75-0(Hazardous Substances Data)

Usage

Description

N-METHYL-N-PHENYLTHIOUREA is an organic compound with the chemical formula C8H10N2S. It is a white crystalline solid that is primarily used as a chemical intermediate in the synthesis of various compounds.

Uses

Used in Chemical Synthesis:
N-METHYL-N-PHENYLTHIOUREA is used as a chemical intermediate for the production of S-Ethyl-N-methyl-N-phenyl-isothiourea, a compound with potential applications in various fields.
Used in Laboratory Applications:
In the presence of solvent acetone, N-METHYL-N-PHENYLTHIOUREA can be heated to produce hydriodide, which may have specific uses in laboratory settings or chemical research.

InChI:InChI=1/C8H10N2S/c1-10(8(9)11)7-5-3-2-4-6-7/h2-6H,1H3,(H2,9,11)

Upstream product

• 4949-94-4 1-benzoyl-3-methyl-3-phenylthiourea 
• 124-41-4 sodium methylate 
• 100-61-8 N-methylaniline 
• 333-20-0 potassium thioacyanate 
• 532-55-8 Benzoyl isothiocyanate 
• 74734-11-5 1H-imidazole-1-carbodithioic acid methyl ester 
• 6544-02-1 silicon tetraisothiocyanate 
• 55246-66-7 Imidazole-1-carbothioic acid methyl-phenyl-amide 
• 66365-41-1 triphenylphosphine-thiocyanogen 
• 40398-25-2 1-Methyl-1-phenyl-3-ethoxycarbonylthioharnstoff 
• 14327-09-4 N-Methyl-N-phenyl-N'-(tert.-butyl)-thioharnstoff 
• 18773-77-8 methyl(phenyl)cyanamide 

Downstream Products

• 51580-78-0 2-(N-methyl-anilino)-5-phenyl-thiazol-4-one 
• 85656-40-2 methyl-(4-methyl-thiazol-2-yl)-phenyl-amine 
• 87944-02-3 ethyl 4-methyl-2-(N-methyl-N-phenylamino)thiazole-5-carboxylate 
• 364356-33-2 ethyl 2-(N-methyl-N-phenylamino)thiazole-4-carboxylate 
• 1369585-67-0 C₁₆H₁₅N₃O₂S₃ 
• 1415819-49-6 C₁₉H₂₀N₄OS 
• 1415820-12-0 4-(2-(methyl(phenyl)amino)thiazol-4-yl)-1H-pyrrole-2-carboxylic acid 
• 82627-81-4 1-Methyl-3-phenyl-imidazolidin-4,5-dion-2-thion 
• 4231-31-6 N-methyl N-phenylamino acetylene 
• 103765-60-2 2-(N-methyl-N-phenylamino)-4-phenylthiazole 
• 1450899-65-6 ethyl (Z)-2-((2-(methyl)(phenyl)amino)thiazol-4-yl)pent-2-enoate 
• 1450899-78-1 ethyl (E)-2-((2-(methyl)(phenyl)amino)thiazol-4-yl)pent-2-enoate 
• 111091-98-6 N-methyl-N-phenylnaphtho[2,1-d]thiazol-2-amine 
• 666820-75-3 (4-methoxy-phenyl)-(3-methyl-3H-benzothiazol-2-ylidene)-amine 

Relevant articles and documents

Sultam thioureas: Synthesis and antiviral activity against west nile virus

The syntheses of eleven sultam thioureas, including nine new compounds, are described. These compounds were synthesized from thioureas and include the first sultam thioureas in which the two thiourea nitrogen groups are not identical. In addition, the first X-ray crystal structures of sultam thioureas and the antiviral activity of these compounds against West Nile virus (WNV) are reported. Georg Thieme Verlag Stuttgart New York.

ION CHANNEL MODULATORS

The present teachings provide carboxylic amide compounds that can modulate the activity of ion channels in a mammal. The present teachings also provide processes for producing said compounds and their pharmaceutically acceptable salts, hydrates and esters, and methods of treating a pathological condition or disorder, or alleviating a symptom thereof, using said compounds including their pharmaceutically acceptable salts, hydrates and esters. The compounds can be useful in modulating ion channel activity including treating a variety of conditions associated with the abnormal modulation of one or more voltage-gated calcium channels.

1-(Methyldithiocarbonyl)imidazole: A useful thiocarbonyl transfer reagent for synthesis of substituted thioureas

1-(Methyldithiocarbonyl)imidazole 1 and its N-methyl quaternary salt 2 have been shown to be efficient methyldithiocarbonyl and thiocarbonyl transfer reagents for the synthesis of dithiocarbamates, symmetrical and unsymmetrical mono-, di- and tri-substituted thioureas in high yields under mild and simple non-hazardous reaction conditions. (C) 2000 Elsevier Science Ltd.