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4106-66-5

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4106-66-5 Usage

Description

3-Aminodibenzofuran, also known as Dibenzo[b,d]furan-3-amine, is an organic compound with a unique chemical structure that features a benzofuran ring system with an amino group attached to the third position. 3-AMINODIBENZOFURAN is known for its potential applications in the pharmaceutical industry due to its ability to interact with various biological targets.

Uses

Used in Pharmaceutical Industry:
3-Aminodibenzofuran is used as a building block for the preparation of dibenzofuryl(phosphonomethyl)alanines, which are known as endothelin converting enzyme (ECE) inhibitors. These inhibitors play a crucial role in the regulation of vascular tone and blood pressure, making them potential therapeutic agents for the treatment of various cardiovascular diseases and conditions related to the renin-angiotensin system.
As a reactant in the synthesis of ECE inhibitors, 3-aminodibenzofuran contributes to the development of novel pharmaceutical compounds that can help in the management and treatment of hypertension, heart failure, and other related cardiovascular disorders. 3-AMINODIBENZOFURAN's unique structure and reactivity make it a valuable component in the design and synthesis of new drugs with improved efficacy and selectivity.

Reactions

Synthesis of Schiff baseEthanolic solutions of 3-aminodibenzofuran and 2-furan carboxaldehyde in 1:1 molar ratio were mixed and refluxed over a water-bath for 3 hours. The resulting Schiff base that separated out on cooling the mixture was filtered, washed with ethanol and air-dried.

Check Digit Verification of cas no

The CAS Registry Mumber 4106-66-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,0 and 6 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4106-66:
(6*4)+(5*1)+(4*0)+(3*6)+(2*6)+(1*6)=65
65 % 10 = 5
So 4106-66-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H9NO/c13-8-5-6-10-9-3-1-2-4-11(9)14-12(10)7-8/h1-7H,13H2

4106-66-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Aminodibenzofuran

1.2 Other means of identification

Product number -
Other names Dibenzo[b,d]furan-3-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4106-66-5 SDS

4106-66-5Relevant articles and documents

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Gilman,Avakian

, p. 349 (1945)

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