41063-39-2

Basic information

• Product Name: 1-(dodecylamino)propan-2-ol
• Synonyms: 1-(dodecylamino)propan-2-ol;1-(Dodecylamino)-2-propanol
• CAS NO: 41063-39-2
• Molecular Formula: C₁₅H₃₃NO
• Molecular Weight: 243.42862
• EINECS: 255-199-9
• Mol File: 41063-39-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 352°Cat760mmHg
• Flash Point: 49°C
• Appearance: /
• Density: 0.86g/cm³
• Vapor Pressure: 2.32E-06mmHg at 25°C
• Refractive Index: 1.454
• CAS DataBase Reference: 1-(dodecylamino)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(dodecylamino)propan-2-ol(41063-39-2)
• EPA Substance Registry System: 1-(dodecylamino)propan-2-ol(41063-39-2)

Safety Data

• Hazardous Substances Data: 41063-39-2(Hazardous Substances Data)

Usage

Description

1-(dodecylamino)propan-2-ol is a chemical compound that consists of a propan-2-ol (isopropanol) molecule with a dodecylamino group attached to it. It is often used as a surfactant or emulsifier in various industrial and commercial applications. The dodecylamino group confers a hydrophobic character to the molecule, making it useful in formulations requiring water-in-oil emulsions or for dispersing hydrophobic substances in aqueous solutions. It can also function as a wetting agent, helping to reduce the surface tension of liquids and improve their spreadability. Additionally, 1-(dodecylamino)propan-2-ol has antimicrobial properties, making it suitable for use in personal care products and cosmetics. Overall, this chemical has diverse applications due to its surfactant, emulsifying, wetting, and antimicrobial properties.

Uses

Used in Personal Care and Cosmetics Industry:
1-(dodecylamino)propan-2-ol is used as an emulsifier for creating water-in-oil emulsions, which are essential in the formulation of various personal care and cosmetic products. Its hydrophobic character allows for the dispersion of hydrophobic substances in aqueous solutions, enhancing the stability and texture of the final product.
Used in Industrial Applications:
1-(dodecylamino)propan-2-ol is used as a surfactant in industrial processes where it helps to reduce the surface tension of liquids, improving their spreadability and facilitating the mixing of different substances. This property is particularly useful in the manufacturing of cleaning agents, detergents, and other products that require efficient dispersion of ingredients.
Used as a Wetting Agent:
1-(dodecylamino)propan-2-ol is used as a wetting agent to improve the spreadability of liquids on surfaces, which can be beneficial in various applications such as agriculture, where it can enhance the distribution of pesticides or fertilizers, or in the textile industry for improving the wetting of fibers during the dyeing process.
Used for Antimicrobial Purposes:
Due to its antimicrobial properties, 1-(dodecylamino)propan-2-ol is used as a preservative in personal care products and cosmetics to prevent the growth of harmful microorganisms, ensuring the safety and shelf life of the products.

InChI:InChI=1/C15H33NO/c1-3-4-5-6-7-8-9-10-11-12-13-16-14-15(2)17/h15-17H,3-14H2,1-2H3

Upstream product

• 78-96-6 3-amino-2-propanol 
• 112-52-7 1-chlorododecane 
• 124-22-1 n-Dodecylamine 
• 75-56-9 methyloxirane 

Relevant articles and documents

Synthesis and Characteristics of Dodecyl Isopropylolamine and Derived Surfactants

Dodecyl isopropylolamine has been synthesized on the basis of dodecylamine and propylene oxide. The structure of dodecyl isopropanolamine has been determined by X-ray diffraction, elemental analysis, IR- and NMR-spectroscopic methods. Ionic surfactants have been synthesized by interaction of dodecyl isopropylolamine with various acids (HCl, HBr, acetic and propionic) and alkyl halides (methyl iodide, ethyl bromide and n-propyl bromide). Colloidal-chemical parameters, petroleum-collecting and petroleum dispersing capacities of the synthesized cationic surfactants have been studied.

Aggregation and antimicrobial properties of gemini surfactants with mono- and di-(2-hydroxypropyl)ammonium head-groups: Effect of the spacer length and computational studies

Cationic gemini surfactants, alkanediyl-α,ω-bis[(2-hydroxypropyl)dodecylammonium] dibromide (abbreviated as C12-s-C12[iso-Pr(OH)] and C12-s-C12[iso-Pr(OH)]2, with s = 2, 3, 4 and 5) have been synthesized, and their aggregation properties in aqueous solution have been studied by surface tension, electrical conductivity and dynamic light scattering methods. On the basis of the results of studying aqueous solutions of the synthesized gemini surfactants by tensiometric and conductometric methods, their principal surfactivity parameters, such as the degree of counterion binding (β), critical micelle concentration (CMC), effectiveness of surface tension reduction (πCMC), surface excess concentration (Γmax), area per molecule at the interface (Amin), changes of Gibbs free energies of adsorption (ΔGad) and micellization (ΔGmic) have been calculated. For both classes of these gemini surfactants, a character of the surfactivity parameters change with an elongation of the spacer chain was defined and comparative analysis with other ammonium-type gemini surfactants having different head-groups was performed. Using dynamic light scattering method, regularities of variation of the aggregates sizes were studied depending on the number of 2-hydroxypropyl groups and the spacer chain length was investigated. Meanwhile, it was revealed that the mentioned gemini surfactants possess antimicrobial properties. The mechanism of the epoxide ring opening and salt formation reactions were calculated by using Kohn–Sham DFT with the B3LYP functional. The epoxide ring opening via primary (dodecylamine) and secondary (INT2) amines was determined as exergonic (13.4 and 4.4 kcal/mol) reactions as observed experimentally.