41109-95-9Relevant articles and documents
Solvent-Free Synthesis of Ethyl α-Cyanocinnamates Catalyzed by K 2O-Al2O3 Using Grinding Method
Wang, Shu-Xiang,Li, Ji-Tai,Yang, Wen-Zhi,Yin, Ya-Hui,Xie, Zi-Hui
, p. 829 - 834 (2004)
K2O-Al2O3 catalyzes the Knoevenagel condensation of ethyl cyanoacetate with aromatic aldehydes, giving ethyl α-cyanocinnamates in 94-98% yield under solvent-free condition by grinding at room temperature.
The Knoevenagel condensation using quinine as an organocatalyst under solvent-free conditions
Jain, Kavita,Chaudhuri, Saikat,Pal, Kuntal,Das, Kalpataru
supporting information, p. 1299 - 1304 (2019/01/21)
The Knoevenagel condensation between active methylene compounds and aromatic carobonyl compounds has been developed using quinine as an organocatalyst to afford various electrophilic alkenes in excellent yields (up to 90%). In the presence of a catalytic amount of quinine (15 mol%), the reaction proceeded at room temperature (RT) under solvent-free conditions. In this green approach, the organocatalyst was recovered and recycled for up to four cycles without appreciable loss of activity.
Aminated poly(vinyl chloride): An efficient green catalyst for Knoevenagel condensation reactions
Rajesh Krishnan,Sree Niveditha,Sreekumar
, p. 428 - 431 (2013/05/08)
Commercially available poly(vinyl chloride) have been modified with ethylene diamine to give a highly efficient reusable organocatalyst for Knoevenagel condensation in water as well as under solvent-less conditions. The reaction proceeds with high yield a
