411235-90-0Relevant articles and documents
Synthesis and pharmacological evaluation of novel cis-3,4-Diaryl-hydroxychromanes as high affinity partial agonists for the estrogen receptor
Bury, Paul S.,Christiansen, Lise B.,Jacobsen, Poul,Jorgensen, Anker S.,Kanstrup, Anders,Narum, Lars,Bain, Steven,Fledelius, Christian,Gissel, Birgitte,Hansen, Birgit S.,Korsgaard, Niels,Thorpe, Susan M.,Wassermann, Karsten
, p. 125 - 145 (2007/10/03)
The syntheses and in vitro pharmacological evaluation of a number of cis-3,4-diaryl-hydroxy-chromanes are reported, along with the results of a thorough in vivo profiling of the tissue-selective estrogen partial-agonist NNC 45-0781 [3, (-)-(3S,4R)-7-hydro