41125-73-9

Basic information

• Product Name: 5-Thiazolecarbonyl chloride (9CI)
• Synonyms: 5-Thiazolecarbonyl chloride (9CI);5-Thiazolecarbonyl chloride;1,3-thiazole-5-carbonyl chloride
• CAS NO: 41125-73-9
• Molecular Formula: C₄H₂ClNOS
• Molecular Weight: 147.58278
• Product Categories: ACIDHALIDE
• Mol File: 41125-73-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 227°Cat760mmHg
• Flash Point: 91.1°C
• Appearance: /
• Density: 1.497g/cm³
• Vapor Pressure: 0.0794mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: 5-Thiazolecarbonyl chloride (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Thiazolecarbonyl chloride (9CI)(41125-73-9)
• EPA Substance Registry System: 5-Thiazolecarbonyl chloride (9CI)(41125-73-9)

Safety Data

• Hazardous Substances Data: 41125-73-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C4H2ClNOS/c5-4(7)3-1-6-2-8-3/h1-2H

Upstream product

• 14527-41-4 thiazole-5-carboxylic acid 

Downstream Products

• 1446442-99-4 N-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]thiazole-5-carboxamide 
• 1383110-64-2 C₂₄H₂₄N₆O₂S 
• 953065-70-8 N-(3-chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)thiazole-5-carboxamide 
• 944909-83-5 thiazole-5-carboxylic acid (4-chloro-2-methyl-phenyl)-amide 

Relevant articles and documents

ACLY INHIBITORS AND USES THEREOF

The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.

HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS

The invention relates to a compound of formula (I) and a racemate, an enantiomer, a diastereoisomer, a geometric isomer or a pharmaceutically acceptable salt thereof, and its use as antibacterial agent.

Synthesis and antibacterial activities of pleuromutilin derivatives with thiazole-5-carboxamide and thioether moiety

Seven novel pleuromutilin derivatives with thiazole-5-carboxamide and thioether moiety in the C14 side chain were designed and synthesised. The antibacterial activities of the target compounds were tested via agar-well diffusion method in vitro. The results showed that three target compounds still had antibacterial activity against Staphylococcus aureus ATCC26112 and Staphylococcus aureus SC at a low concentration of 0.05 μg mL-1.