4116-10-3 Usage
Description
2-CHLORO-N-METHYLACETOACETAMIDE is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and chemical compounds. It is characterized by its reactivity and functional groups, which make it a versatile building block in the development of new drugs and materials.
Uses
Used in Pharmaceutical Industry:
2-CHLORO-N-METHYLACETOACETAMIDE is used as a synthetic intermediate for the preparation of piperidinylmethyl (thiazolyl)phenylcarbamates. These compounds are valuable as M3 muscarinic acetylcholine receptor antagonists, which play a crucial role in the treatment of chronic obstructive lung diseases, chronic bronchitis, asthma, and other related conditions. The antagonistic action of these compounds helps to alleviate symptoms and improve the quality of life for patients suffering from these respiratory ailments.
Check Digit Verification of cas no
The CAS Registry Mumber 4116-10-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,1 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4116-10:
(6*4)+(5*1)+(4*1)+(3*6)+(2*1)+(1*0)=53
53 % 10 = 3
So 4116-10-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H8ClNO2/c1-3(8)4(6)5(9)7-2/h4H,1-2H3,(H,7,9)
4116-10-3Relevant articles and documents
A convenient method for reduction dehalogenation of α-halocarbonyl compounds using benzenethiol in K+/CH3CN system
Dong, Wei-Li,Cai, Wen-Xi,Wu, Rui,Li, Zheng-Ming,Zhao, Wei-Guang,Liu, Xing-Hai
, p. 980 - 983 (2016/07/06)
Benzenethiol, as a reductive agent for the dehalogenation of various α-halocarbonyl compounds, is investigated in the K+/CH3CN system. The reaction affords the reduced compounds in high yields under mild reaction conditions, especially α-chlorocarbonyl compounds. Furthermore, the reaction performed under ultrasonic irradiation greatly shortens the reaction time.