4117-14-0 Usage
Description
2-Decyn-1-ol is an organic compound with a unique structure featuring an alkyne group and a hydroxyl group. It is a versatile building block in the synthesis of various biologically active molecules, particularly in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
2-Decyn-1-ol is used as a key intermediate in the synthesis of antitumor agents, specifically isomers of Panaxytriol and Falcarinol (F101100). These compounds have shown potential in the treatment of various types of cancer due to their ability to interfere with cancer cell growth and proliferation.
Additionally, 2-Decyn-1-ol is used as a starting material in the synthesis of aromatase inhibitors. Aromatase inhibitors are a class of drugs that are primarily used in the treatment of hormone receptor-positive breast and ovarian cancers. By inhibiting the enzyme aromatase, these drugs reduce the production of estrogen, which can help slow down or stop the growth of cancer cells that rely on this hormone for survival.
Check Digit Verification of cas no
The CAS Registry Mumber 4117-14-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,1 and 7 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4117-14:
(6*4)+(5*1)+(4*1)+(3*7)+(2*1)+(1*4)=60
60 % 10 = 0
So 4117-14-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H18O/c1-2-3-4-5-6-7-8-9-10-11/h11H,2-7,10H2,1H3
4117-14-0Relevant articles and documents
Sex attractants of geometrid and noctuid moths: Chemical characterization and field test of monoepoxides of 6,9-dienes and related compounds
Ando,Kishi,Akashio,Qin Xu-Rong,Saito,Abe,Hashimoto
, p. 299 - 311 (1995)
-
Total syntheses of 9-epoxyfalcarindiol and its diastereomer
Zhou, Yun,Huang, Yanli,Li, Shuoning,Yang, Pengfei,Zhong, Jiangchun,Yin, Jingwei,Ji, Kaijie,Yang, Yanqing,Ye, Ning,Wang, Lifeng,Wang, Mingan,Wang, Min,Bian, Qinghua
, p. 288 - 295 (2017/02/18)
The first total syntheses of 9-epoxyfalcarindiol 1a and its diastereomer 1b have been achieved. Central to our approach were the Zn-cyclopropane-based amino alcohol catalyzed enantioselective alkynylation of acrolein, the diastereoselective addition of a diynic ester to an epoxy aldehyde, and the asymmetric Sharpless epoxidation of allylic alcohol catalyzed with L-(+)-diethyl tartrate and Ti(OiPr)4.
Tetris in monolayers: Patterned self-assembly using side chain shape
Xue, Yi,Zimmt, Matthew B.
supporting information; experimental part, p. 8832 - 8834 (2011/09/16)
The "kinked" shapes of conjugated alkadiynes constrain chain packing in monolayers on HOPG. Centrally located diyne units permit assembly of 1,5-bis(alkadiyne)anthracene monolayers. Off-center diynes inhibit self-assembly. Shape matched pairs of off-center diyne chains direct self-assembly of compositionally patterned, two component monolayers.