41171-91-9 Usage
Description
3-Oxo-cyclopentanecarbonitrile, also known as 3-Cyanocyclopentanone, is an alicyclic ketone that features a cyclopentanone structure with a cyano group substitution at the 3rd position. This organic compound is characterized by its unique chemical properties and potential applications in various industries.
Uses
Used in Chemical Synthesis:
3-Oxo-cyclopentanecarbonitrile is utilized as an intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical and chemical industries. Its unique structure allows for further functionalization and modification, making it a valuable building block for the development of new molecules with specific properties and applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Oxo-cyclopentanecarbonitrile is used as a key intermediate in the synthesis of various drug molecules. Its reactivity and structural diversity enable the development of novel therapeutic agents with improved efficacy and selectivity.
Used in Catalytic Enantioselective Conjugate Addition:
3-Oxo-cyclopentanecarbonitrile is employed as a reactant in the catalytic enantioselective conjugate addition of cyanide to enones. This process is crucial for the synthesis of chiral molecules with high enantiomeric purity, which are essential in the development of enantiomerically pure drugs and other biologically active compounds.
Synthesis Reference(s)
The Journal of Organic Chemistry, 38, p. 3455, 1973 DOI: 10.1021/jo00960a002
Check Digit Verification of cas no
The CAS Registry Mumber 41171-91-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,1,7 and 1 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 41171-91:
(7*4)+(6*1)+(5*1)+(4*7)+(3*1)+(2*9)+(1*1)=89
89 % 10 = 9
So 41171-91-9 is a valid CAS Registry Number.
41171-91-9Relevant articles and documents
Direct C(sp3)-H Cyanation Enabled by a Highly Active Decatungstate Photocatalyst
Kim, Kunsoon,Lee, Seulchan,Hong, Soon Hyeok
supporting information, p. 5501 - 5505 (2021/07/26)
A highly efficient, direct C(sp3)-H cyanation was developed under mild photocatalytic conditions. The method enabled the direct cyanation of various C(sp3)-H substrates with excellent functional group tolerance. Notably, complex natural products and bioactive compounds were efficiently cyanated.
D3 RECEPTOR AGONIST COMPOUNDS; METHODS OF PREPARATION; INTERMEDIATES THEREOF; AND METHODS OF USE THEREOF
-
Paragraph 0159; 0168, (2020/10/21)
Disclosed herein are novel compounds including dopamine D3 receptor agonists, compositions thereof, methods of use thereof, and processes of synthesizing the same. Further disclosed are D3R selective agonist compounds, specifically bitopic ligands comprising chirality.
Preparation of chiral 3-oxocycloalkanecarbonitrile and its derivatives by crystallization-induced diastereomer transformation of ketals with chiral 1,2-diphenylethane-1,2-diol
Yamashita, Yohei,Maki, Daisuke,Sakurai, Shiho,Fuse, Takumi,Matsumoto, Shoji,Akazome, Motohiro
, p. 32601 - 32609 (2018/10/15)
Chiral 3-oxocycloalkanecarbonitriles were prepared by fractional crystallization and crystallization-induced diastereomer transformation (CIDT) of diastereomeric ketals with (1R,2R)-1,2-diphenylethane-1,2-diol. Investigation of the crystal structures by X
