41199-19-3 Usage
Description
1,2,3,4,4a,5,6,7-Octahydro-2,5,5-trimethyl-2-naphthol is a colorless to pale yellow liquid with an extremely powerful, amber, somewhat musty and animal odor. It is a constituent of ambergris and is synthesized through a process that starts with the thermolysis of β-ionone, leading to dehydroambrinol. 1,2,3,4,4a,5,6,7-Octahydro-2,5,5-trimethyl-2-naphthol is then obtained by hydrogenation over Raney nickel in a methanolic solution.
Uses
Used in Perfumery:
1,2,3,4,4a,5,6,7-Octahydro-2,5,5-trimethyl-2-naphthol is used as a fixative and fragrance ingredient in the perfumery industry for its powerful, amber, somewhat musty, and animal odor. It is used in small amounts in all perfume types to enhance and prolong the scent of various products.
Used in Cosmetics:
1,2,3,4,4a,5,6,7-Octahydro-2,5,5-trimethyl-2-naphthol is used as a fragrance ingredient in the cosmetics industry, contributing to the overall scent profile of products such as lotions, creams, and other personal care items.
Used in Soaps:
In the soap industry, 1,2,3,4,4a,5,6,7-Octahydro-2,5,5-trimethyl-2-naphthol is used as a fragrance ingredient to provide a unique and powerful scent to soap products.
Used in Body Care Products:
1,2,3,4,4a,5,6,7-Octahydro-2,5,5-trimethyl-2-naphthol is used as a fragrance ingredient in body care products, such as body lotions, shower gels, and other personal care items, to enhance their scent and provide a pleasant user experience.
Used in Detergents:
In the detergent industry, 1,2,3,4,4a,5,6,7-Octahydro-2,5,5-trimethyl-2-naphthol is used as a fragrance ingredient to add a distinct and powerful scent to laundry detergents and other cleaning products.
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 41199-19-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,1,9 and 9 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 41199-19:
(7*4)+(6*1)+(5*1)+(4*9)+(3*9)+(2*1)+(1*9)=113
113 % 10 = 3
So 41199-19-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H22O/c1-12(2)7-4-5-10-9-13(3,14)8-6-11(10)12/h5,11,14H,4,6-9H2,1-3H3
41199-19-3Relevant articles and documents
Titanium-catalyzed enantioselective synthesis of α-ambrinol
Justicia, Jose,Campan, Araceli G.,Bazdi, Btissam,Robles, Rafael,Cuerva, Juan M.,Oltra, J. Enrique
experimental part, p. 571 - 576 (2009/05/07)
We describe the first enantioselective synthesis of the odorant compound (-)-α-ambrinol (96% ee) from commercial geranylacetone. The key steps are a Jacobsen's asymmetric epoxidation and a titanium-catalyzed stereoselective cyclization initiated by radical epoxide opening. The oxirane ring opening proceeds with retention of configuration at the epoxide chiral center, giving a secondary alcohol which can be advantageously exploited to raise the ee provided by the synthetic sequence. We also synthesized (+)-α-ambrinol by a closely related procedure, showing the synthetic versatility of combining titanium-catalyzed cyclization with Jacobsen's epoxidation reactions.
New Synthesis of γ-Homocyclogeranial, γ-Dihydroionone and Their Derivatives
Kawanobe, Tsuneo,Kogami, Kunio,Hayashi, Kazuo,Matsui, Masanao
, p. 461 - 464 (2007/10/02)
A new and efficient synthesis of γ-homocyclogeranial (4), γ-dihydroionone (3) and their derivatives, 5, 6, 7 and 8, volatile components of ambergris, is described.Their compounds were synthesized via Claisen rearrangement of (3,3-dimethylcyclohexenyl)methyl vinyl ether (14).
SYNTHESIS OF (+/-)-α-AMBRINOL
Takazawa, Osamu,Tamura, Hiroshi,Kogami, Kunio,Hayashi, Kazuo
, p. 1257 - 1258 (2007/10/02)
Synthesis of α-ambrinol was successfully accomplished by cyclization of dihydro-γ-ionone ethylene acetal which was prepared by the titanium(IV)-promoted reaction of 3,3-dimethyl-1-trimethylsiloxycyclohexene with methyl vinyl ketone ethylene acetal followed by exomethylenation with triphenylphosphonium methylide.
