4120-05-2

Basic information

• Product Name: 4,6-DiphenylpyriMidin-2-ol
• Synonyms: 4,6-Diphenyl-2(1H)-pyrimidinone;4,6-Diphenylpyrimidin-2-one;2(1H)-Pyrimidinone, 4,6-diphenyl-;2-hydoxy-4,6-diphenyl-pyrimidine;4,6-DiphenylpyriMidin-2-ol
• CAS NO: 4120-05-2
• Molecular Formula: C₁₆H₁₂N₂O
• Molecular Weight: 248.27928
• Mol File: 4120-05-2.mol
• Article Data: 26

Chemical Properties

• Melting Point: 230-232 °C
• Appearance: /
• Density: 1.17±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 8.46±0.10(Predicted)
• CAS DataBase Reference: 4,6-DiphenylpyriMidin-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-DiphenylpyriMidin-2-ol(4120-05-2)
• EPA Substance Registry System: 4,6-DiphenylpyriMidin-2-ol(4120-05-2)

Safety Data

• Hazardous Substances Data: 4120-05-2(Hazardous Substances Data)

Usage

General Description

4,6-DiphenylpyriMidin-2-ol is a chemical compound with the molecular formula C17H13N3O. It belongs to the class of pyrimidine derivatives and is characterized by a pyrimidine ring structure with two phenyl groups attached at positions 4 and 6. 4,6-DiphenylpyriMidin-2-ol has been used in various pharmaceutical and research applications, including as a building block in the synthesis of various biologically active compounds. Its unique structure and properties make it a valuable intermediate in organic synthesis and medicinal chemistry. 4,6-DiphenylpyriMidin-2-ol has also been investigated for potential pharmacological activities, making it an interesting target for further research and development.

Upstream product

• 111862-38-5 2-Nitroso-4,6-diphenyl-pyrimidine 
• 87275-43-2 4,6-diphenyl-5-bromo-5,6-dihydropyrimidine-2(1H)-one 
• 120-46-7 1,3-diphenylpropanedione 
• 57-13-6 urea 
• 2915-16-4 2-chloro-4,6-diphenylpyrimidine 
• 7338-94-5 1,3-diphenyl-2-propynone 
• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 94-41-7 benzalacetophenone 
• 611-91-6 2,3-dibromo-1,3-diphenylpropane-1-one 
• 106119-61-3 2-Hydroxyamino-4,6-diphenylpyrimidine 
• 4113-79-5 4,6-diphenyl-3,4-dihydropyrimidin-2(1H)-one 
• 100-44-7 benzyl chloride 
• 585-71-7 (1-bromoethyl)benzne 

Downstream Products

• 46898-00-4 4,6-diphenyl-1,2-dihydropyrimidine 
• 2915-16-4 2-chloro-4,6-diphenylpyrimidine 
• 1417444-59-7 1-2',3',5'-tri-O-benzoyl-β-D-ribopentofuranosyl-4,6-diphenylpyrimidin-2-thione 
• 32079-26-8 4,6-diphenyl-5,6-dihydropyrimidine-2(1H)-thione 
• 1417444-55-3 1-2',3',5'-tri-O-benzoyl-α-D-ribopentofuranosyl-4,6-diphenylpyrimidin-2-one 
• 1417444-56-4 1-2',3',5'-tri-O-benzoyl-β-D-ribo-pentofuranosyl-4,6-diphenylpyrimidin-2-one 
• 135587-61-0 4,4',6,6'-tetraphenyl-2,2'-bipyrimidine 
• 66758-83-6 (4,6-diphenyl-pyrimidin-2-yl)-ethyl-amine 
• 81668-44-2 N-Butyl-N-(4,6-diphenyl-pyrimidin-2-yl)-4-methyl-benzamide 
• 81668-43-1 N-(4,6-Diphenyl-pyrimidin-2-yl)-4-methyl-N-propyl-benzamide 
• 81668-42-0 N-(4,6-Diphenyl-pyrimidin-2-yl)-N-ethyl-4-methyl-benzamide 
• 81668-41-9 (4,6-Diphenyl-pyrimidin-2-yl)-methyl-phenyl-amine 
• 81668-40-8 N-butyl-4,6-diphenylpyrimidin-2-amine 
• 81668-39-5 (4,6-Diphenyl-pyrimidin-2-yl)-propyl-amine 

Relevant articles and documents

Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors

Presently, artemisinin-based combination therapy (ACT) is the first-line therapy of Plasmodium falciparum malaria. With the emergence of malaria parasites that are resistant to ACT, alternative antimalarial therapies are urgently needed. In line with this

Synthesis of 4,6-diarylpyrimidin-2(1H)-one derivatives from benzyl halides and (1-bromoethyl)benzene under solvent-free conditions

A facile synthesis of a series of pyrimidinone derivatives from the reaction of benzyl halides, (1-bromoethyl)benzene and urea in the presence of pyridine N-oxide (PNO) under solvent-free conditions is described. This transformation presumeably occurs via oxidation/cross-aldol condensation/Michael addition/intra molecular cyclization, domino sequence, involving the formation of one C–C bond and two C–N bonds in a single step.

Photo-dehydrogenation of 4,6-diaryl-2-oxo-1,2,3,4-tetrahydropyrimidines

Electron-transfer-induced photo-oxidation of 4,6-diaryl-substituted 2-oxo-1,2,3,4-tetrahydropyrimidines (THPMs) in chloroform under argon atmosphere results in the smooth formation of 4,6-diaryl-substituted 2-oxo-1,2-dihydropyrimidines. Sequentially, elec