412012-08-9

Basic information

• Product Name: 3-methoxy-1,2-diphenyl-1-propanone
• Synonyms: 3-methoxy-1,2-diphenyl-1-propanone
• CAS NO: 412012-08-9
• Molecular Weight: 240.302
• Mol File: 412012-08-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-methoxy-1,2-diphenyl-1-propanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methoxy-1,2-diphenyl-1-propanone(412012-08-9)
• EPA Substance Registry System: 3-methoxy-1,2-diphenyl-1-propanone(412012-08-9)

Safety Data

• Hazardous Substances Data: 412012-08-9(Hazardous Substances Data)

Upstream product

• 858000-20-1 3-methoxy-2-phenyl-propionyl chloride 
• 71-43-2 benzene 
• 451-40-1 phenyl benzyl ketone 
• 67-56-1 methanol 
• 94-41-7 benzalacetophenone 
• 4452-11-3 1,2-diphenylprop-2-en-1-one 

Downstream Products

• 4452-11-3 1,2-diphenylprop-2-en-1-one 

Relevant articles and documents

A triphenylphosphine mediated photo-rearrangement and methanol addition of aryl chalcones to 1-propanones

Aryl chalcones rearrange and add methanol to give substituted propane-1-ones upon UV-A irradiation in the presence of PPh3. We propose two possible mechanisms for this photo-rearrangement. The reaction involves either the formation of a phosphi

Cobalt-Catalyzed α-Methoxymethylation and Aminomethylation of Ketones with Methanol as a C1 Source

Using methanol as a sustainable C1 source, cobalt-catalyzed α-methoxymethylation and α-aminomethylation of ketones have been developed. With cheap CoCl2·6H2O as catalyst and TBHP as oxidant, the methoxymethylated products were obtained within a short reaction time in up to 91% yield. Based on the observed reversibility of methoxy adduct to enone, the α-aminomethylation of ketones was then achieved by a one-pot methylenation/aza-Michael addition sequence. In addition, an easy way to convert α-methoxymethyl ketones to α-aminomethyl ketones has been discovered.