412299-83-3

Basic information

• Product Name: Benzoic acid, 2-benzoyl-4-bromo-
• Synonyms: Y6221
• CAS NO: 412299-83-3
• Molecular Formula: C14H9BrO3
• Molecular Weight: 305.128
• Mol File: 412299-83-3.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-benzoyl-4-bromo-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-benzoyl-4-bromo-(412299-83-3)
• EPA Substance Registry System: Benzoic acid, 2-benzoyl-4-bromo-(412299-83-3)

Safety Data

• Hazardous Substances Data: 412299-83-3(Hazardous Substances Data)

Upstream product

• 71-43-2 benzene 
• 86-90-8 4-bromophthalic anhydride 
• 100-58-3 phenylmagnesium bromide 
• 95-50-1 1,2-dichloro-benzene 
• 156001-51-3 3-Bromo-6-methyl-benzonitrile 
• 64-19-7 acetic acid 
• 7446-70-0 aluminium trichloride 
• 439937-52-7 (5-bromo-2-methylphenyl)(phenyl)methanone 

Downstream Products

• 586-76-5 4-Bromobenzoic acid 
• 65-85-0 benzoic acid 
• 447423-12-3 6-bromo-4-phenyl-1H-isochromene-3-carboxylic acid 
• 718620-10-1 N-(2-hydroxyethyl)-N-methyl-2-benzoyl-4-bromobenzamide 
• 718620-11-2 N-(2-hydroxyethyl)-N-methyl-2-benzoyl-5-bromobenzamide 
• 1557155-02-8 2-[(3-cyano-2-isobutyl-1-oxo-4-phenyl-1,2-dihydro-6-isoquinolinyl)oxy]acetamide 
• 447416-95-7 2-{[3-(aminomethyl)-2-isobutyl-1-oxo-4-phenyl-1,2-dihydro-6-isoquinolinyl]oxy}acetamide 
• 447417-81-4 6-bromo-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile 
• 838840-98-5 6-tert-butoxy-2-isobutyl-1-oxo-4-phenyl-1,2-dihydro-3-isoquinolinecarbonitrile 
• 1557155-00-6 6-hydroxy-2-isobutyl-1-oxo-4-phenyl-1,2-dihydro-3-isoquinolinecarbonitrile 
• 447425-19-6 C₂₀H₁₉BrN₂O₂ 
• 583834-70-2 3-amino-2-benzyl-6-bromo-4-phenyl-2-isoquinolin-1-one 
• 1227079-49-3 (2-benzyl-6-bromo-1-oxo-4-phenyl-1,2-dihydroisoquinolin-3-yl)carbamic acid benzyl ester 
• 583838-25-9 2-benzoyl-4-bromo-N-(4-methoxybenzyl)-N-(2-oxobutyl)benzamide 

Relevant articles and documents

Synthesis of isoindoles by one-electron reductions of dibenzo[1,4]diazocines

A synthetic protocol to isoindoles is reported through one-electron reductions of dibenzo[1,4]diazocines. The utility of the approach has been demonstrated through the synthesis of six novel isoindole derivatives. Photophysical measurements revealed emissions between 440 and 460 nm. A reaction mechanism, supported by experimental results and quantum chemical calculations, is postulated.

INDOLINONE ANALOGUES AS BRD4 INHIBITORS

The present invention encompasses compounds of general formula (I) wherein the groups R1 to R4, A1 and A2 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament.

Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: A new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554

The design, synthesis, and structure-activity relationships of a new class of potent and orally active non-peptide dipeptidyl peptidase IV (DPP-4) inhibitors, 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones, are described. We hypothesized that the 4-ph