4125-98-8

Basic information

• Product Name: H-MEILE-OH
• Synonyms: N-ALPHA-METHYL-L-ISOLEUCINE;N-ME-ILE-OH;N-ME-ISOLEUCINE;N-METHYL-L-ISOLEUCINE;H-MELLE-OH;H-MEILE-OH;N-a-Methyl-L-isoleucine;H-L-MeIle-OH
• CAS NO: 4125-98-8
• Molecular Formula: C₇H₁₅NO₂
• Molecular Weight: 145.2
• Product Categories: N-Methyl Amino Acids;Peptide Synthesis;Unnatural Amino Acid Derivatives;amino acid;amino acids
• Mol File: 4125-98-8.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 226.1±23.0 °C(Predicted)
• Appearance: /
• Density: 0.979±0.06 g/cm3(Predicted)
• Storage Temp.: Store at RT.
• PKA: 2.50±0.24(Predicted)
• CAS DataBase Reference: H-MEILE-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-MEILE-OH(4125-98-8)
• EPA Substance Registry System: H-MEILE-OH(4125-98-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 4125-98-8(Hazardous Substances Data)

Usage

General Description

I sincerely apologize, but there's no currently known chemical with the name "H-MEILE-OH" existing in any database or scientific literature I could find. The name does not seem to correspond to any standard notation for chemical compounds. If it is a shorthand or specific code used in certain research contexts, you might require more specific details or context. The chemical might be a specific type of amino acid sequence, peptide, or other type of molecule, but without further context, it's challenging to provide a precise interpretation or summary. You may want to check the spelling or the source of the chemical's name.

Upstream product

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Downstream Products

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• 220663-32-1 <2-C(S)>-Fmoc-NMeIle-Thr(Ψ^H,pmppro)-OBn 
• 820972-74-5 N-Nitroso-N-methyl-L-isoleucyl-D-α-hydroxy-isovaleriansaeure-(4-nitro-benzylester) 
• 50673-48-8 N-methyl-D-allo-isoleucine 

Relevant articles and documents

Komesuamide and odopenicillatamide, two linear lipopeptides from the marine cyanobacterium Caldora penicillata

The linear lipopeptides komesuamide (1) and odopenicillatamide (2) were isolated from Caldora penicillata a marine cyanobacterium collected in Okinawa. The structures of these compounds were established by spectroscopic analyses, and the absolute configurations were determined by HPLC analyses of the acid hydrolysates. Both compounds showed glucose uptake activity at 40 μM in cultured L6 myotubes.

Isolation and structure elucidation of cyclopeptide alkaloids from the leaves of Heisteria parvifolia

Heisteria parvifolia Sm. is prescribed in traditional medecine against numerous diseases in C?te d'Ivoire. Due to the shortcoming in scientifical knowledge of use of this species, our investigations revealed five undescribed cyclopeptide alkaloids added to one known derivative namely anorldianine. These compounds were elucidated by 1D and 2D-NMR experiments and comparison with literature data, and confirmed by HR-ESI-MS. Cytotoxic activity evaluation of these compounds against the chronic myeloid leukemia (K565) cell line exhibited an antiproliferative activity with cell growth inhibition from 13% to 46%.

Odobromoamide, a terminal alkynyl bromide-containing cyclodepsipeptide from the marine cyanobacterium okeania sp.

The bioassay-guided fractionation of the Okinawan marine cyanobacterium Okeania sp. led to the isolation of the novel cyclodepsipeptide odobromoamide (1). The gross structure of 1 was determined by spectroscopic analyses, and its absolute stereochemistry was determined using a variety of different methods, including chemical derivatization and degradation followed by HPLC analysis. In addition, odobromoamide (1) exhibited broad-spectrum cytotoxicity against a human cancer cell line panel.