41259-67-0

Basic information

• Product Name: N4-BUTYL-6-CHLORO-PYRIMIDINE-4,5-DIAMINE
• Synonyms: N4-BUTYL-6-CHLORO-PYRIMIDINE-4,5-DIAMINE;IFLAB-BB F2124-0087;N4-Butyl-6-chloro-4,5-pyrimidinediamine;(5-amino-6-chloro-pyrimidin-4-yl)-butyl-amine;4-N-butyl-6-chloropyrimidine-4,5-diamine
• CAS NO: 41259-67-0
• Molecular Formula: C₈H₁₃ClN₄
• Molecular Weight: 200.67
• Mol File: 41259-67-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 351.7 °C at 760 mmHg
• Flash Point: 166.5 °C
• Appearance: /
• Density: 1.261 g/cm³
• CAS DataBase Reference: N4-BUTYL-6-CHLORO-PYRIMIDINE-4,5-DIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N4-BUTYL-6-CHLORO-PYRIMIDINE-4,5-DIAMINE(41259-67-0)
• EPA Substance Registry System: N4-BUTYL-6-CHLORO-PYRIMIDINE-4,5-DIAMINE(41259-67-0)

Safety Data

• Hazardous Substances Data: 41259-67-0(Hazardous Substances Data)

Usage

General Description

N4-BUTYL-6-CHLORO-PYRIMIDINE-4,5-DIAMINE is a chemical compound with the molecular formula C9H14ClN5. It is a pyrimidine derivative with a butyl group attached to the nitrogen atom at position 4 and a chlorine atom attached to position 6. The compound has two amine groups located at positions 4 and 5 of the pyrimidine ring. This chemical may have potential applications in pharmaceuticals, agrochemicals, or material science due to its unique structure and functional groups. Further research and studies may be required to fully understand its properties and potential uses.

Upstream product

• 5413-85-4 5-amino-4,6-dichloropyridimine 
• 109-73-9 N-butylamine 
• 492464-18-3 butyl-(6-chloro-5-nitro-pyrimidin-4-yl)-amine 

Downstream Products

• 5444-84-8 9-butyl-1,9-dihydro-purin-6-one 
• 5444-83-7 9-butyl-6-chloro-9H-purine 
• 521308-60-1 N-(4-butylamino-6-chloropyrimidin-5-yl)-2-(2,5-dimethoxyphenyl)acetamide 
• 1246291-42-8 3-(6-(butylamino)-4-chloropyrimidin-5-ylamino)cyclohex-2-enone 
• 521308-67-8 9-butyl-8-(3-methoxybenzyl)-9H-purin-6-ylamine 
• 352519-21-2 9-butyl-8-(3,4,5-trimethoxy-benzyl)-9H-purin-6-ylamine 

Relevant articles and documents

Orally active purine-based inhibitors of the heat shock protein 90

Orally active Hsp90 inhibitors are of interest as potential chemotherapeutic agents. Recently, fully synthetic 8-benzyladenines and 8-sulfanyladenines such as 4 were disclosed as Hsp90 inhibitors, but these compounds are not water soluble and consequently

An efficient one-pot synthesis of 6-alkoxy-8,9-dialkylpurines via reaction of 5-amino-4-chloro-6-alkylaminopyrimidines with N,N-dimethylalkaneamides and alkoxide ions

The synthesis of a number of new 6-alkoxy-8,9-(disubstituted)purines has been accomplished by the cyclization of the corresponding intermediate 5-amino-4-chloro-6-(alkylamino)pyrimidines promoted by alkoxides and various N,N-dimethyl amides, where the latter act as solvent-reagents. By this three-component condensation reaction we are able to introduce an alkyl group in the 8 position of the purine ring with the concomitant nucleophilic replacement of the 6-chloro group with an alkoxy moiety.