41296-38-2

Basic information

• Product Name: 2,6-Bis-(4-chloro-phenyl)-4-oxo-cyclohexane-1,1-dicarboxylic acid dimethyl ester
• Synonyms: 2,6-Bis-(4-chloro-phenyl)-4-oxo-cyclohexane-1,1-dicarboxylic acid dimethyl ester
• CAS NO: 41296-38-2
• Molecular Weight: 435.304
• Mol File: 41296-38-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,6-Bis-(4-chloro-phenyl)-4-oxo-cyclohexane-1,1-dicarboxylic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Bis-(4-chloro-phenyl)-4-oxo-cyclohexane-1,1-dicarboxylic acid dimethyl ester(41296-38-2)
• EPA Substance Registry System: 2,6-Bis-(4-chloro-phenyl)-4-oxo-cyclohexane-1,1-dicarboxylic acid dimethyl ester(41296-38-2)

Safety Data

• Hazardous Substances Data: 41296-38-2(Hazardous Substances Data)

Downstream Products

• 222529-12-6 2,6-bis-(4-chloro-phenyl)-4-oxo-cyclohexanecarboxylic acid 
• 222529-16-0 2,6-bis-(4-chloro-phenyl)-cyclohexane-1,4-dione 

Relevant articles and documents

Michael addition approach for the synthesis of novel spiro compounds and 2-substituted malonic acid derivatives from Meldrum's acid

Novel routes for the synthesis of spiro derivatives of Meldrum's acid and 2-substituted malonic acid derivatives have been developed. Meldrum's acid was monoalkylated using a Michael addition reaction. Mono-Michael adducts were then alkylated using substituted haloalkanes, which on condensation gave spiro derivatives of Meldrum's acid. Bis Michael addition of Meldrum's acid with 1,5-diaryl-1,4-pentadien-3-one gave directly a spiro derivative of Meldrum's acid. These compounds and bis alkylated Meldrum's acid derivatives, on acidic methanolysis gave 2-substituted malonic acids.