41327-15-5

Basic information

• Product Name: 5-BROMO-3-METHYL-1-PHENYLPYRAZOLE
• Synonyms: 5-BROMO-3-METHYL-1-PHENYLPYRAZOLE;5-broMo-3-Methyl-1-phenyl-1H-pyrazole
• CAS NO: 41327-15-5
• Molecular Formula: C₁₀H₉BrN₂
• Molecular Weight: 237.09586
• Mol File: 41327-15-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 312.5 °C at 760 mmHg
• Flash Point: 142.8 °C
• Appearance: /
• Density: 1.45 g/cm³
• Vapor Pressure: 0.000968mmHg at 25°C
• Refractive Index: 1.625
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-BROMO-3-METHYL-1-PHENYLPYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-3-METHYL-1-PHENYLPYRAZOLE(41327-15-5)
• EPA Substance Registry System: 5-BROMO-3-METHYL-1-PHENYLPYRAZOLE(41327-15-5)

Safety Data

• Hazardous Substances Data: 41327-15-5(Hazardous Substances Data)

Usage

General Description

5-Bromo-3-methyl-1-phenylpyrazole is a chemical compound with the molecular formula C10H9BrN2. It is a substituted pyrazole derivative that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 5-BROMO-3-METHYL-1-PHENYLPYRAZOLE has potential applications in the development of novel drugs and crop protection products due to its unique structure and reactivity. It may also be used as a research tool in the field of organic chemistry and drug discovery. The presence of a bromine atom and a methyl group in the molecule imparts specific properties and reactivity to the compound, making it valuable for various industrial and scientific purposes. Overall, 5-Bromo-3-methyl-1-phenylpyrazole is a versatile chemical with potential applications in the fields of medicine, agriculture, and research.

InChI:InChI=1/C10H9BrN2/c1-8-7-10(11)13(12-8)9-5-3-2-4-6-9/h2-7H,1H3

Upstream product

• 1131-18-6 1-Phenyl-3-methyl-5-aminopyrazole 
• 591-50-4 iodobenzene 
• 5744-68-3 5-bromo-3-methyl-1H-pyrazole 
• 89-25-8 edaravone 
• 19735-89-8 3-methyl-1-phenylpyrazolin-5(4H)-one 
• 7789-60-8 phosphorus tribromide 
• 74-96-4 ethyl bromide 
• 1131-17-5 5-chloro-3-methyl-1-phenyl-1H-pyrazole 

Downstream Products

• 1128-54-7 3-methyl-1-phenyl-1H-pyrazole 
• 760937-92-6 3-{(2S,4S)-1-(1,1-dimethylethyloxycarbonyl)-4-[4-(3-methyl-1-phenyl-1H-pyrazole-5-yl)piperazin-1-yl]pyrrolidine-2-ylcarbonyl}thiazolidine 
• 401566-79-8 1-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazine 
• 401566-80-1 tert-butyl (2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]-2-(1,3-thiazolidin-3-ylcarbonyl)pyrrolidine-1-carboxylate 
• 52943-87-0 5-bromo-3-methyl-1-(4-nitro-phenyl)-1H-pyrazole 
• 91211-33-5 4,5-Dibrom-3-methyl-1-phenyl-pyrazol 

Relevant articles and documents

Direct Transformation of Arylamines to Aryl Halides via Sodium Nitrite and N-Halosuccinimide

A one-pot universal approach for transforming arylamines to aryl halides via reaction with sodium nitrite (NaNO2) and N-halosuccinimide (NXS) in DMF at room temperature under metal- and acid-free condition is described. This new protocol that is complementary to the Sandmeyer reaction, is suggested to involve the in situ generation of nitryl halide induce nitrosylation of aryl amine to form the diazo intermediate which is halogenated to furnish the aryl halide.

Teneligliptin key intermediate preparation method

The present invention discloses a preparation method of a teneligliptin key intermediate 1-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazine (compound I), and belongs to the technical field of medicine preparation. According to the method of the present inven