4135-11-9 Usage
Description
Polymyxin B(1) is a type of polymyxin, a class of antibiotics, characterized by the presence of a (6R)-6-methyloctanoyl group at the amino terminus. It is known for its potent antibacterial properties and is particularly effective against multidrug-resistant gram-negative bacterial infections.
Uses
Used in Pharmaceutical Industry:
Polymyxin B(1) is used as an antibacterial agent for the treatment of patients with multidrug-resistant gram-negative bacterial infections. Its high volume of distribution and longer elimination half-life contribute to its effectiveness in combating these infections.
Additionally, due to its potent antibacterial properties, polymyxin B(1) may also be used in other applications such as:
Research and development for new antimicrobial agents
Topical applications for skin infections
Veterinary medicine for treating bacterial infections in animals
However, it is important to note that the specific uses mentioned in the provided materials are limited to its role as an antibacterial compound in the pharmaceutical industry. Further research and development may reveal additional applications for polymyxin B(1) in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 4135-11-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,3 and 5 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4135-11:
(6*4)+(5*1)+(4*3)+(3*5)+(2*1)+(1*1)=59
59 % 10 = 9
So 4135-11-9 is a valid CAS Registry Number.
InChI:InChI=1/C56H98N16O13/c1-7-32(4)13-11-12-16-44(75)63-36(17-23-57)51(80)72-46(34(6)74)56(85)68-39(20-26-60)48(77)67-41-22-28-62-55(84)45(33(5)73)71-52(81)40(21-27-61)65-47(76)37(18-24-58)66-53(82)42(29-31(2)3)69-54(83)43(30-35-14-9-8-10-15-35)70-49(78)38(19-25-59)64-50(41)79/h8-10,14-15,31-34,36-43,45-46,73-74H,7,11-13,16-30,57-61H2,1-6H3,(H,62,84)(H,63,75)(H,64,79)(H,65,76)(H,66,82)(H,67,77)(H,68,85)(H,69,83)(H,70,78)(H,71,81)(H,72,80)/t32-,33-,34-,36+,37+,38+,39+,40-,41+,42+,43+,45+,46+/m1/s1
4135-11-9Relevant articles and documents
Polymyxin B conjugates
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, (2008/06/13)
Compositions and methods are described for preventing and treating sepsis in humans and other animals. Surgical patients, low birth weight infants, burn and trauma victims, as well as other individuals at risk can be treated prophylactically. Methods for treating acute infections with advantages over current therapeutic approaches are provided.
Radiopharmaceutical bacteriostats
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, (2008/06/13)
Benzalkonium chloride and benzethorium chloride are each useful in radiopharmaceutical preparations (optionally in the presence of a polymyxin or a polymyxin derivative) as bacteriostatic agents which are compatible with anti-oxidants.