41398-19-0Relevant articles and documents
The palladium catalysed biaryl cross-coupling of pyridazine triflates
Aldous,Bower,Moorcroft,Todd
, p. 150 - 152 (2001)
The scope of trifluoromethanesulfonic acid 6-methyl-pyridazine-3-yl ester as a coupling partner for biaryl synthesis via palladium catalysed Suzuki and Stille coupling conditions is reported.
Thulium Triflate Catalyzed Hydration of 2-Substituted 4-Alkynones
Chang,Cheng
supporting information, p. 1931 - 1935 (2016/08/09)
We report on a facile synthetic route for the preparation of substituted 1,4-diketones by thulium triflate mediated hydration of substituted 4-alkynones in MeNO2 at 25 °C for five hours. The products were obtained in moderate to high yields.
From N-sulfonyl,C-homoallyl-hydrazones to pyrazole and pyridazine (N 2)-heterocycles: The ultimate aromatization process
Mboyi, Cleve Dionel,Duhayon, Carine,Canac, Yves,Chauvin, Remi
, p. 4957 - 4968 (2014/07/07)
Isomeric six- and five-membered (N2)-aromatics, 6-methylpyridazines and 5-vinylpyrazoles, which energetic topological aromaticity is comparable to that of benzene, are shown to be efficiently produced by sequential isomerization-elimination processes from the corresponding 6-methylidene-1,4,5,6-tetrahydropyridazines and 5-vinylpyrazolines, respectively. The latter precursors are available from the same N-sulfonyl,C-homoallyl-hydrazone substrates by a suitable choice of previously reported conditions for Pd-catalyzed CH-oxidative C,N-ring closing processes. The generality of these cyclization, isomerization, and aromatization reactions, for which detailed mechanisms are proposed, provides a systematic access to wide ranges of 3,4,6-trisubstituted 6-methyl-1,4-dihydropyridazines and 6-methylpyridazines, and their 3,4,5-trisubstituted 5-vinylpyrazole isomers.