4141-12-2

Basic information

• Product Name: Benzoic acid, 2-[[(methylamino)carbonyl]amino]-
• Synonyms: Benzoic acid, 2-[[(methylamino)carbonyl]amino]-;2-(3-Methylureido)benzoic acid
• CAS NO: 4141-12-2
• Molecular Formula: C9H10N2O3
• Molecular Weight: 194
• Mol File: 4141-12-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Benzoic acid, 2-[[(methylamino)carbonyl]amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-[[(methylamino)carbonyl]amino]-(4141-12-2)
• EPA Substance Registry System: Benzoic acid, 2-[[(methylamino)carbonyl]amino]-(4141-12-2)

Safety Data

• Hazardous Substances Data: 4141-12-2(Hazardous Substances Data)

Usage

General Description

Benzoic acid, 2-[[(methylamino)carbonyl]amino]- is a chemical compound with the molecular formula C9H9NO4. It is a derivative of benzoic acid and is commonly used as an intermediate in the production of pharmaceuticals and agrochemicals. Benzoic acid, 2-[[(methylamino)carbonyl]amino]- is also known for its potential use in the treatment of various diseases, particularly as an anti-inflammatory and anti-microbial agent. It has also been studied for its potential role in the development of new drugs for the treatment of cancer and other disorders. Additionally, its properties as a food preservative make it a common additive in various food products.

Upstream product

• 118-48-9 isatoic anhydride 
• 593-51-1 methylamine hydrochloride 
• 118-92-3 anthranilic acid 
• 624-83-9 methyl isocyanate 
• 74-89-5 methylamine 

Downstream Products

• 607-19-2 3-methyl-2,4(1H,3H)-quinazolinedione 

Relevant articles and documents

Synthesis and evaluation of highly selective quinazoline-2,4-dione ligands for sphingosine-1-phosphate receptor 2

A series of twenty-nine new quinazoline-2,4-dione compounds were synthesized and their IC50 values for binding toward sphingosine-1-phosphate receptor 2 (S1PR2) were determined using a [32P]S1P binding assay. Seven compounds 2a, 2g, 2h, 2i, 2j, 2k, and 5h exhibit high S1PR2 binding potencies (IC50 values 98%), and high molar activity (153-222 GBq μmol-1, at the end of bombardment). [11C]2a and [11C]2i were further evaluated by the ex vivo biodistribution study. The results showed that both tracers have low brain uptake, preventing their potential for neuroimaging application. Further explorations of this class of S1PR2 PET tracers in peripheral tissue diseases are underway. This journal is

New sedative and hypotensive 3-substituted 2,4(1H,3H)-quinazolinediones.

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