41421-03-8

Basic information

• Product Name: 2-(4-BROMOPHENYL)-5-METHYL-1,3,4-OXADIAZOLE
• Synonyms: 2-(4-BROMOPHENYL)-5-METHYL-1,3,4-OXADIAZOLE;2-(4-bromophenyl)-5-methyl-1,3,4-oxadiazole(SALTDATA: FREE);1,3,4-Oxadiazole, 2-(4-bromophenyl)-5-methyl-
• CAS NO: 41421-03-8
• Molecular Formula: C₉H₇BrN₂O
• Molecular Weight: 239.08
• Mol File: 41421-03-8.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 327.9°C at 760 mmHg
• Flash Point: 152.1°C
• Appearance: /
• Density: 1.528g/cm³
• Vapor Pressure: 0.000375mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: 2-(4-BROMOPHENYL)-5-METHYL-1,3,4-OXADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-BROMOPHENYL)-5-METHYL-1,3,4-OXADIAZOLE(41421-03-8)
• EPA Substance Registry System: 2-(4-BROMOPHENYL)-5-METHYL-1,3,4-OXADIAZOLE(41421-03-8)

Safety Data

• Hazardous Substances Data: 41421-03-8(Hazardous Substances Data)

Usage

General Description

2-(4-Bromophenyl)-5-methyl-1,3,4-oxadiazole is a chemical compound with the molecular formula C9H7BrN2O. It is a heterocyclic organic compound that contains both nitrogen and oxygen atoms in its five-membered ring structure. 2-(4-BROMOPHENYL)-5-METHYL-1,3,4-OXADIAZOLE is commonly used in the field of medicinal chemistry and pharmaceutical research due to its potential biological activities, including antimicrobial and antifungal properties. It can also be used as a building block in the synthesis of various pharmaceutical drugs and agrochemicals. Additionally, it has been studied for its potential application as a fluorescent probe in biological imaging techniques.

InChI:InChI=1/C9H7BrN2O/c1-6-11-12-9(13-6)7-2-4-8(10)5-3-7/h2-5H,1H3

Upstream product

• 50907-23-8 5-(4-bromophenyl)-1H-tetrazole 
• 108-24-7 acetic anhydride 
• 119072-55-8 tert-butylisonitrile 
• 589-87-7 1,4-bromoiodobenzene 
• 1068-57-1 acetic acid hydrazide 
• 78-39-7 Triethyl orthoacetate 
• 5933-32-4 4-bromobenzoic acid hydrazide 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 127-19-5 N,N-dimethyl acetamide 
• 50907-23-8 1-bromo-4-(2H-tetrazol-5-yl)benzene 
• 18871-66-4 N,N-dimethylacetamide dimethyl acetal 
• 25408-61-1 Ν,Ν-dimethylacetamide dimethyl acetal 
• 595565-71-2 acetic acid (4-bromobenzylidene)-hydrazide 
• 74038-71-4 N’-acetyl-4-bromobenzohydrazide 

Downstream Products

• 848952-81-8 3-(4-bromophenyl)-4-(4-methoxyphenyl)-5-methyl-4H-[1,2,4]triazole 
• 1453853-23-0 (2R,3S,4R,5S,6R)-2-(hydroxymethyl)-6-[3-[2-[4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]ethynyl]phenyl]tetrahydropyran-3,4,5-triol 
• 911062-27-6 2-(2'-methoxybiphenyl-4-yl)-5-methyl-1,3,4-oxadiazole 
• 179056-82-7 4-(5-methyl-1,3,4-oxadiazol-2-yl)benzaldehyde 

Relevant articles and documents

The preparation, characterization and catalytic activity of Ni NPs supported on porous alginate-g-poly(p-styrene sulfonamide-co-acrylamide)

Herein, we report the synthesis of nickel nanoparticles under mild conditions using porous alginate-g-poly(p-styrene sulfonamide-co-acrylamide) as a protecting/stabilizing agent and sodium borohydride as a reducing agent. The porous cross-linked polymeric support was preparedviacombining the use of sol-gel, nanocasting, and crosslinking techniques, in which thep-styrene sulfonamide monomer (PSSA) andN,N′-methylene-bis (acrylamide) (MBA) cross-linker underwent copolymerization on the surface of sodium alginate in the presence of a SiO2nanoparticle (NP) template (Alg-PSSA-co-ACA). The prepared catalyst (Alg-PSSA-co-ACA@Ni) showed high catalytic activity for the one-step synthesis of 1,3,4-oxadiazoles from the reaction of hydrazides and aryl iodides through isocyanide insertion/cyclization.

One-pot synthesis of 2,5-disubstituted-1,3,4-oxadiazoles based on the reaction of N,N-dimethyl amides with acid hydrazides

Convenient and efficient one pot method for the synthesis of 2,5-disubstituted-1,3,4-oxadiazoles based on the reaction of N,N-dimethyl amides with acid hydrazides has been developed. The methodology is applied to a wide range of difference aryl hydrazide and difference N,N-dimethyl amides to 2,5-disubstituted-1,3,4-oxadiazoles yield the in good to excellent yields. It will be possible wide useful application in synthesis. Synopsis Convenient and efficient one pot method for the synthesis of 2,5-disubstituted-1,3,4- oxadiazoles based on the reaction of N,N-dimethyl amides with acid hydrazides has been developed. The methodology is applied to a wide range of difference aryl hydrazide and difference N,N-dimethyl amides to 2,5-disubstituted- 1,3,4-oxadiazoles yield the in good to excellent yields. It will be possible wide useful application in synthesis. Copyright

NOVEL PHENYLPROPIONIC ACID DERIVATIVES AS PEROXISOME PROLIFERATOR-ACTIVATED GAMMA RECEPTOR MODULATORS, METHOD OF THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention provides a novel phenylpropionic acid derivative and a PPAR-γ modulator comprising the same as an active ingredient. The phenylpropionic acid derivative of the present invention has modulatory action on function of PPAR-γ and then exhibits hypoglycemic, hypolipidemic and insulin resistance-reducing effects on PPAR-mediated diseases or disorders. Therefore, the present invention is prophylactically or therapeutically effective for diabetes and metabolic diseases.