4144-14-3

Basic information

• Product Name: L-Threonine, O-methyl-N-[(phenylmethoxy)carbonyl]-, methyl ester
• CAS NO: 4144-14-3
• Molecular Formula: C14H19NO5
• Molecular Weight: 281.309
• Mol File: 4144-14-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: L-Threonine, O-methyl-N-[(phenylmethoxy)carbonyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Threonine, O-methyl-N-[(phenylmethoxy)carbonyl]-, methyl ester(4144-14-3)
• EPA Substance Registry System: L-Threonine, O-methyl-N-[(phenylmethoxy)carbonyl]-, methyl ester(4144-14-3)

Safety Data

• Hazardous Substances Data: 4144-14-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 83824-81-1 (2S,3S)-3-methylaziridine-1,2-dicarboxylic acid 1-benzylester 2-methyl ester 
• 501-53-1 benzyl chloroformate 
• 57224-63-2 methyl (2S,3R)-2-(benzyloxycarbonylamino)-3-hydroxybutyrate 
• 74-88-4 methyl iodide 
• 83860-98-4 (2S,3S)-H-3-MeAzy-OMe 

Downstream Products

• 4144-02-9 O-methyl-L-threonine 

Relevant articles and documents

Synthesis of Nitriles from Aldoximes and Primary Amides Using XtalFluor-E

The dehydration reaction of aldoximes and amides for the synthesis of nitriles using [Et2NSF2]BF4 (XtalFluor-E) is described. Overall, the reaction proceeds rapidly (normally 1 h) at room temperature in an environmentally benign solvent (EtOAc) with only a slight excess of the dehydrating agent (1.1 equiv). A broad scope of nitriles can be prepared, including chiral nonracemic ones. In addition, in a number of cases, further purification of the nitrile after the workup was not required.

Novel jadomycins: Incorporation of non-natural and natural amino acids

Electrospray ionization mass spectrometry of extracts from Streptomyces venezuelae ISP5230 cultures grown on chemically synthesized non-natural l-amino acids, d-amino acids or any of the 20 natural amino acids demonstrated incorporation of the amino acid into a jadomycin B analogue.