41492-05-1 Usage
Description
1-Bromo-4-butylbenzene is an organic compound that belongs to the class of bromoarenes. It is a clear colorless to yellow liquid and is characterized by the presence of a bromine atom attached to a butylbenzene molecule. 1-Bromo-4-butylbenzene is known for its versatile chemical properties and is widely utilized in various applications across different industries.
Uses
1. Used in Organic Synthesis:
1-Bromo-4-butylbenzene is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows it to participate in a range of chemical reactions, making it a valuable building block for the creation of complex molecules.
2. Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-Bromo-4-butylbenzene is used as a starting material for the preparation of various drugs and drug candidates. Its reactivity and structural diversity enable the development of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
3. Used in Chemical Intermediates for Liquid Crystals:
1-Bromo-4-butylbenzene is also utilized as an intermediate in the production of liquid crystals. These liquid crystals are essential components in the manufacturing of display technologies, such as televisions, computer monitors, and smartphones.
4. Used in Catalysts for Suzuki-Miyaura Reaction:
The phosphite or phosphine oxide ligand catalyzed Suzuki-Miyaura reaction of 2-pyridyl boron derivatives with 1-bromo-4-butylbenzene has been reported. This reaction is a significant method in organic chemistry for the formation of carbon-carbon bonds, particularly in the synthesis of complex organic molecules and pharmaceuticals.
5. Used in the Preparation of Monomers for Polymers:
1-Bromo-4-butylbenzene is used as a monomer in the preparation of poly(4-butyltriphenylamine), a polymer with potential applications in various fields, such as electronics and materials science.
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 41492-05-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,4,9 and 2 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 41492-05:
(7*4)+(6*1)+(5*4)+(4*9)+(3*2)+(2*0)+(1*5)=101
101 % 10 = 1
So 41492-05-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H13Br/c1-2-3-4-9-5-7-10(11)8-6-9/h5-8H,2-4H2,1H3
41492-05-1Relevant articles and documents
Synthesis method of p-bromo-linear alkylbenzene
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Paragraph 0035; 0049, (2017/08/25)
The invention belongs to the technical field of fine chemical industry, and in particular discloses a clean and efficient synthetic process technology of p-bromo-linear alkylbenzene. Paradibromobenzene and linear chain 1-haloalkane are added into an organic solvent, and reaction is conducted under the action of a catalyst ferric acetylacetonate and an activating agent consisting of zinc halide and magnesium powder to obtain the p-bromo-linear alkylbenzene. A paradibromobenzene single coupling technology is adopted, so production of ortho/meta isomers which are difficult to separate is avoided from the source; a Grignard reagent, which is instable to water and air, or an expensive boric acid reagent intermediate is not used, so that the production cost is reduced; a one-pot reaction technology is adopted, so that operation is simplified and good industrial application value is achieved.
Two flavors of PEPPSI-IPr: Activation and diffusion control in a single NHC-ligated Pd catalyst?
Larrosa, Igor,Somoza, Clara,Banquy, Alexandre,Goldup, Stephen M.
supporting information; experimental part, p. 146 - 149 (2011/03/20)
Abnormal reactivity has been observed in Negishi, Suzuki-Miyaura, and Kumada-Tamao-Corriu cross-couplings in which PEPPSI-IPr (where PEPPSI stands for pyridine enhanced precatalyst preparation, stabilization, and initiation and IPr refers to the NHC ligand) is employed, implicating the presence of two distinct Pd0 species in the catalytic cycle. Polybrominated arenes and organometallic reagents react selectively to give the product of exhaustive polysubstitution regardless of the initial reaction stoichiometry. Competition experiments suggest that, after an initial activation controlled oxidative addition, reductive elimination produces an ultrareactive Pd0 species which consumes all remaining C-Br bonds in the molecule under diffusion control.
Palladium-catalyzed cross-coupling alkylation of arenediazonium o-benzenedisulfonimides
Barbero, Margherita,Cadamuro, Silvano,Dughera, Stefano
, p. 474 - 478 (2008/09/21)
Arenediazonium o-benzenedisulfonimides were reacted with tetramethyltin, tetrabutyltin or trialkylboranes. The reactions, carried out in the presence of palladium(II) derivatives as precatalysts, gave the methylation and alkylation products with good over
