41610-76-8Relevant articles and documents
ANTIFUNGAL COMPOUNDS DERIVED FROM LAVENDER OIL
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Paragraph 0113-0114, (2020/03/23)
Epoxides and hydroperoxide compounds having antifungal activities derived from the oxidation linalyl acetate, a major component of lavender oil, are disclosed. Also, disclosed are pharmaceutical composition and methods of treating and protecting a subject from fungal infection.
Catalytic homogeneous oxidation of monoterpenes and cyclooctene with hydrogen peroxide in the presence of sandwich-type tungstophosphates [M4(H2O)2(PW9O34)2]n?, M = CoII, MnII and FeIII
Santos, Isabel C.M.S.,Gamelas, José A.F.,Duarte, Tiago A.G.,Sim?es, Mário M.Q.,Neves, M. Gra?a P.M.S.,Cavaleiro, José A.S.,Cavaleiro, Ana M.V.
, p. 593 - 599 (2016/12/16)
Catalytic efficiency of tetrabutylammonium salts of sandwich tungstophosphates B‐α‐[M4(H2O)2(PW9O34)2]n?, M = CoII, MnII, FeIII, was studied in the oxidation of (R)-(+)-limonene, geraniol, linalool, linalyl acetate, carveol, and cis-cyclooctene with hydrogen peroxide, in acetonitrile. Oxidation of (R)-(+)-limonene gave limonene-1,2-diol as main product. Epoxidation of linalool takes place preferentially at the more substituted 6,7-double bond, the corresponding 6,7-epoxide reacting further, yielding furano- and pyrano-oxides, via intramolecular cyclization. Oxidation of linalyl acetate occurred preferentially at the more substituted 6,7-double bond for Mn4(PW9)2, affording 6,7-epoxide at 82% selectivity. Linalyl acetate 1,2-epoxide was the major product with 51% and 77% selectivity for Co4(PW9)2 and Fe4(PW9)2, respectively. Oxidation of carveol occurred with very good conversions in the presence of Mn4(PW9)2, Co4(PW9)2 and Fe4(PW9)2, yielding carvone and carveol 1,2-epoxide in similar amounts. Oxidation of cis-cyclooctene gave only the epoxide, while oxidation of geraniol at room temperature afforded 2,3-epoxygeraniol as the major product.
Catalytic performance of a boron peroxotungstate complex under homogeneous and heterogeneous conditions
Santos, Isabel C.M.S.,Balula, Salete S.,Sim?es, Mário M.Q.,Cunha-Silva, Luís,Neves, M. Gra?a P.M.S.,De Castro, Baltazar,Cavaleiro, Ana M.V.,Cavaleiro, José A.S.
, p. 87 - 94 (2013/08/24)
The preparation and characterization (FT-IR, FT-Raman, 11B MAS NMR, diffuse reflectance, elemental analysis) of a novel boron peroxotungstate (BTBA)4H[BW4O24] (BTBA = benzyltributylammonium) is reported, along with its use in the homogeneous oxidation of cis-cyclooctene, geraniol, linalool and (-)-carveol with H 2O2 as oxidant and acetonitrile as solvent. High catalytic activity was registered for all the substrates studied under homogeneous conditions, namely 99% of conversion of geraniol after 2 h, 93% for linalool after 5 h, 74% for cis-cyclooctene after 6 h, and 100% for (-)-carveol after 2 h of reaction. Some oxidation studies were carried out with the Venturello complex, [PW4O24]3-, in the same conditions. Furthermore, the boron peroxotungstate (BW4) was immobilized using two different strategies: (a) BW4 anchored into a functionalized silica (aptesSiO2) giving BW4@aptesSiO2 and (b) BW4 encapsulated on a metal organic framework, commonly referred as MIL-101, giving BW4@MIL-101. The catalytic activity of both heterogeneous materials was investigated for geraniol oxidation and the results were compared with those obtained with BW4 under homogeneous conditions. The encapsulated boron peroxotungstate (BW4@MIL-101) gave rise to the best results, reaching complete conversion of geraniol after 3 h of reaction and 78% selectivity for 2,3-epoxygeraniol. Additionally, this heterogeneous catalyst could be reused without appreciable loss of catalytic activity, affording similar 2,3-epoxygeraniol selectivity. The heterogeneous catalysts' stability was also investigated after the oxidation reactions by different characterization techniques.
