41640-76-0

Basic information

• Product Name: dibenzylcadaverine
• Synonyms: dibenzylcadaverine
• CAS NO: 41640-76-0
• Molecular Formula: C₁₉H₂₆N₂
• Molecular Weight: 282.42
• Mol File: 41640-76-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: dibenzylcadaverine(CAS DataBase Reference)
• NIST Chemistry Reference: dibenzylcadaverine(41640-76-0)
• EPA Substance Registry System: dibenzylcadaverine(41640-76-0)

Safety Data

• Hazardous Substances Data: 41640-76-0(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 111-24-0 1,5-dibromo-pentane 
• 100-46-9 benzylamine 
• 19925-33-8 1-<(Benzoyloxy)phenylmethyl>pyridinium-chlorid 
• 19946-76-0 7-Phenyl-6-aza-2,4,6-heptatrienal 
• 462-94-2 1,5-diaminopentane 
• 19946-77-1 1,9-Diphenyl-2,8-diaza-nonatetraen-(2,4cis,6cis,8) 
• 6958-80-1 NN'-di(benzylidene)-1,5-diaminopentane 
• 628-77-3 1,5-diiodopentane 

Downstream Products

• 1311508-47-0 C₂₇H₃₄N₂O₆ 
• 201148-41-6 N,N'-bis(4-quinolinyl)-N,N'-dibenzylpentane-1,5-diamine 
• 102292-17-1 C₄₁H₅₄N₂O₂ 
• 101632-78-4 N,N'-Bis-<2-hydroxy-aethyl>-N,N'-dibenzyl-1,5-diamino-pentan 
• 1413576-43-8 2-(benzyl(5-(benzyl(2-(cyclohexylamino)-2-oxoethyl)amino)pentyl)amino)-N-(3,4,5-trimethoxyphenyl)acetamide 
• 1413576-24-5 2,2'-(pentane-1,5-diylbis(benzylazanediyl))bis(N-cyclohexylacetamide) 
• 1413576-21-2 2,2'-(pentane-1,5-diylbis(benzylazanediyl))bis(N-pentylacetamide) 
• 500542-86-9 N,N'-Bis-<2-chlor-aethyl>-N,N'-dibenzyl-1,5-diamino-pentan 

Relevant articles and documents

The scale-up of continuous biphasic liquid/liquid reactions under super-heating conditions: Methodology and reactor design

Biphasic liquid/liquid reactions are commonplace, however their scale-up under super-heating conditions is not. Even more challenging efforts have to be expected in the case of a large scale continuous production process, which also includes the development at a lab scale, the selection and design of the continuous reaction equipment. However, by running chemistry above the boiling point of the solvent, the solvent selection can be widened to include green solvents and continuous processing guarantees a limited and safe footprint. Herein is reported a systematic methodology for the development and scale-up of a biphasic reaction under super-heating conditions, as well as the design of a continuous reactor column suitable for handling such conditions. Taking the alkylation of benzylamine with 1,5-dibromopentane as a model reaction, kinetic determination and fluid dynamic characterization of the biphasic media have been instrumental for a successful scale-up concept which was proven in a custom-made hastelloy reactor column.

Design, synthesis and biological activity of peptidomimetic analogs of insect allatostatins

Allatostatins (ASTs) comprise a family of insect neuropeptides isolated from cockroaches and found to inhibit the production of juvenile hormone (JH) by the corpora allata (CA). For this reason, the ASTs can be regarded as possible IGR candidates for pest control. Six peptidomimetic analogs according to the C-terminal pentapeptide of ASTs were prepared by solid-phase organic synthetic methods in an attempt to obtain new simple substitution agents. Assays of inhibition of JH biosynthesis in vitro by corpora allata from the cockroach Diploptera punctata showed that the activity of analog I (IC50: 0.09 μM) was more active than that of the C-terminal pentapeptide (Tyr-Xaa-Phe-Gly-Leu-NH2, IC50: 0.13 μM) it mimicked and the activity of the analog II (IC50: 0.13 μM) proved roughly equivalent to the C-terminal pentapeptide. The results indicate that a new simple mimicry for Tyr-Xaa-Phe-Gly has been discovered; analog I may be a novel compound candidate for potential IGRs. This study will be useful for the design of new AST analogs for insect management.

Di-adamantane derivatives of α,ω-polymethylenediamines with antimicrobial activity

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