41679-15-6

Basic information

• Product Name: (S)-2-aMino-3-(4-hydroxy-3-(hydroxyMethyl)phenyl)propanoic acid
• Synonyms: (S)-2-aMino-3-(4-hydroxy-3-(hydroxyMethyl)phenyl)propanoic acid;L-4-Hydroxy-3-hydroxymethylphenylalanine
• CAS NO: 41679-15-6
• Molecular Formula: C₁₀H₁₃NO₄
• Molecular Weight: 211.21452
• Mol File: 41679-15-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: >300℃
• Appearance: /
• Density: 1.411
• CAS DataBase Reference: (S)-2-aMino-3-(4-hydroxy-3-(hydroxyMethyl)phenyl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-aMino-3-(4-hydroxy-3-(hydroxyMethyl)phenyl)propanoic acid(41679-15-6)
• EPA Substance Registry System: (S)-2-aMino-3-(4-hydroxy-3-(hydroxyMethyl)phenyl)propanoic acid(41679-15-6)

Safety Data

• Hazardous Substances Data: 41679-15-6(Hazardous Substances Data)

Usage

General Description

(S)-2-amino-3-(4-hydroxy-3-(hydroxymethyl)phenyl)propanoic acid, also known as dopa, is a chemical compound that plays a crucial role in the biosynthesis of neurotransmitters like dopamine, epinephrine, and norepinephrine. It is a non-essential amino acid that is synthesized from the amino acid phenylalanine. Dopa is important in the treatment of Parkinson's disease, as it is a precursor to dopamine, a neurotransmitter that is depleted in patients with this condition. Additionally, dopa has been studied for its potential neuroprotective and antioxidant properties, and it may have applications in treating other neurodegenerative disorders. Furthermore, dopa is also used in the production of melanin, the pigment responsible for the color of skin, hair, and eyes, showcasing the diverse range of functions this chemical compound has in the human body.

Upstream product

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• 698386-61-7 benzyl (S)-4-(4H-1,3-benzodioxin-6-ylmethyl)-5-oxo-1,3-oxazolane-3-carboxylate 

Relevant articles and documents

A convenient two step transformation of tyrosine into the antihypertensive amino acid (S)-4-hydroxy-3-hydroxymethylphenylalanine

Treatment of tyrosine with paraformaldehyde and catalytic amounts of p-toluenesulfonic acid, at reflux in toluene, directly generates benzyl (S)-4-(4H-1,3-benzodioxin-6-ylmethyl)-5-oxo-1,3-oxazolane-3-carboxylate, which on treatment with boron trichloride in dichloromethane, affords (S)-4-hydroxy-3-hydroxymethylphenylalanine.

L-3-hydroxymethyltyrosine and salts thereof for lowering blood pressure

L-3-Hydroxymethyltyrosine and pharmaceutically acceptable salts thereof useful in lowering blood pressure and compositions thereof.