41697-19-2

Basic information

• Product Name: N-Salicyloyl-N'-benzoylhydrazine
• Synonyms: 1-Salicyloyl-2-benzoylhydrazine;N'-Benzoylsalicylic hydrazide;N-Salicyloyl-N'-benzoylhydrazine
• CAS NO: 41697-19-2
• Molecular Formula: C₁₄H₁₂N₂O₃
• Molecular Weight: 256.2567
• Mol File: 41697-19-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 540.4°Cat760mmHg
• Flash Point: 280.6°C
• Appearance: /
• Density: 1.304g/cm³
• CAS DataBase Reference: N-Salicyloyl-N'-benzoylhydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Salicyloyl-N'-benzoylhydrazine(41697-19-2)
• EPA Substance Registry System: N-Salicyloyl-N'-benzoylhydrazine(41697-19-2)

Safety Data

• Hazardous Substances Data: 41697-19-2(Hazardous Substances Data)

Upstream product

• 532-32-1 sodium benzoate 
• 98-88-4 benzoyl chloride 
• 936-02-7 2-Hydroxybenzoylhydrazine 
• 69-72-7 salicylic acid 
• 65-85-0 benzoic acid 
• 119-36-8 methyl salicylate 
• 142273-50-5 Z-2-methoxycarbonylmethylene-5-phenyl-2,3-dihydro-3-furanone 
• 198974-12-8 2-[2-(4-chlorophenyl)-2-oxoethylidene]-5-phenylfuran-3(2H)-one 

Downstream Products

• 18233-24-4 2-(5-phenyl-1,3,4-oxadiazol-2-yl)phenol 
• 1523272-57-2 2-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl benzoate 

Relevant articles and documents

[30]metallacrown-10 compounds: [mn(c14h9n2o3) (ch3oh) ] 10·5ch2cl2· 16 ch3oh·h2o and [fe(c14h9n2o3) (ch3ch) ] 10·3ch2cl2· 12.5 Ch3oh·5h2o

A plauar decanuclear 30-membered core ring is present in the new manganese (see picture) and iron [30]azametallacrown-10 compounds. These compounds were prepared by using the pentadentate ligand N-phenylsalicylhydrazidate, and the metal atoms in each ring adopt a propeller configuration and have alternating Λ/Δ stereochemistries.

Chemistry of 2-ylidenefuran-3(2H)-ones: XIX. Reaction of 5-aryl-2(oxoylidene)furan-3(2H)-ones with carboxylic acid hydrazides

2-[2-(4-Chlorophenyl)-2-oxoethylidene]-5-phenylfuran-3(2H)-one and methyl (5-aryl-3-oxo-2,3-dihydrofuran-2-ylidene)acetates react with carboxylic acid hydrazides to give the corresponding 3-substituted 2-acyl-6-aryl-3-hydroxy-2,3- dihydropyridazin-4(1H)-ones. Specificities of the product structure are discussed.

Pentafluorophenyl ester activation for the preparation of N,N'-diaroylhydrazines

Procedures are reported for the preparation of N,N'-diaroylhydrazines using pentafluorophenyl (Pfp) ester activation of aryl carboxylic acids. Mild conditions which avoid intermediate protection of ring substituents, allows the synthesis of both symmetrical and unsymmetrical diaroylhydrazines in high yields. The recent discovery of potent HIV-1 integrase inhibition by N,N'-bis-salicylhydrazine (1) highlights the potential importance of this class of compounds. The stability of pre-activated Pfp ester intermediates and the facility with which N,N'-diaroylhydrazines can be synthesized using this procedure (stirring at room temperature in DMF) may make the method particularly attractive for synthesis of hydrazide libraries.