41727-17-7

Basic information

• Product Name: DIBUTYL 2,6-PYRIDINEDICARBOXYLATE, 99
• Synonyms: DIBUTYL 2,6-PYRIDINEDICARBOXYLATE, 99;dibutyl 2,6-pyridinedicarboxylate;dibutyl pyridine-2,6-dicarboxylate;2,6-Pyridinedicarboxylic acid dibutyl ester;Pyridine-2,6-dicarboxylic acid dibutyl ester;Einecs 255-519-7
• CAS NO: 41727-17-7
• Molecular Formula: C₁₅H₂₁NO₄
• Molecular Weight: 279.33154
• EINECS: 255-519-7
• Mol File: 41727-17-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 66-68 °C(lit.)
• Boiling Point: 400.7°C at 760 mmHg
• Flash Point: 196.1°C
• Appearance: /
• Density: 1.084g/cm³
• Vapor Pressure: 1.25E-06mmHg at 25°C
• Refractive Index: 1.499
• CAS DataBase Reference: DIBUTYL 2,6-PYRIDINEDICARBOXYLATE, 99(CAS DataBase Reference)
• NIST Chemistry Reference: DIBUTYL 2,6-PYRIDINEDICARBOXYLATE, 99(41727-17-7)
• EPA Substance Registry System: DIBUTYL 2,6-PYRIDINEDICARBOXYLATE, 99(41727-17-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 41727-17-7(Hazardous Substances Data)

Usage

Description

DIBUTYL 2,6-PYRIDINEDICARBOXYLATE, 99 is a chemical compound with a purity of 99%, known for its excellent solubility in organic solvents and its ability to enhance the flexibility and durability of various materials.

Uses

Used in Plasticizer Industry:
DIBUTYL 2,6-PYRIDINEDICARBOXYLATE, 99 is used as a plasticizer in various products such as adhesives, sealants, and coatings. It helps to improve the flexibility and durability of these materials.
Used in Pharmaceutical and Agrochemical Industries:
DIBUTYL 2,6-PYRIDINEDICARBOXYLATE, 99 is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, contributing to the development of new and effective products in these fields.
It is important to handle DIBUTYL 2,6-PYRIDINEDICARBOXYLATE, 99 with care and follow safety precautions to avoid any potential hazards.

InChI:InChI=1/C15H21NO4/c1-3-5-10-19-14(17)12-8-7-9-13(16-12)15(18)20-11-6-4-2/h7-9H,3-6,10-11H2,1-2H3

Upstream product

• 499-83-2 Pyridine-2,6-dicarboxylic acid 
• 71-36-3 butan-1-ol 
• 5453-67-8 2,6-bis(methoxycarbonyl)pyridine 
• 2402-78-0 2,6-dichloropyridine 
• 201230-82-2 carbon monoxide 
• 626-05-1 2,6-Dibromopyridine 

Downstream Products

• 1195-59-1 2.6-bis(hydroxymethyl)pyridine 
• 112633-26-8 2,6-bis[(tosyloxy)methyl]pyridine 

Relevant articles and documents

Palladium-Catalyzed Butoxycarbonylation of Polybromo(hetero)arenes: A Practical Method for the Preparation of (Hetero)arenepolycarboxylates and -carboxylic Acids

The palladium-catalyzed alkoxycarbonylation of polybromo (hetero)arenes was investigated systematically. The results show that cheap and readily available in situ Pd(OAc) 2/ rac -BINAP catalyst can catalyze the butoxycarbonylation of various polybromo(hetero)arenes efficiently, and gave (hetero)arenepolycarboxylates with moderate to high yield (59-94%). Using this method, two new compounds, 4,4'-bis(butoxycarbonyl)-1,1'-bi-2-naphthol and dibutyl [2,2'-bipyrimidine]-5,5'-dicarboxylate, are reported for the first time. In addition, the gram-scale preparation of carboxylate and carboxylic acids was successful performed by butoxycarbonylation followed by hydrolysis. This shows the wide scope of substrates and practical applications of the Pd(OAc) 2/ rac -BINAP catalytic system. Moreover, these carboxylic acids and carboxylates can be used as ligands or structural units to construct MOFs, metal complexes, and COFs etc.

Transesterification of various methyl esters under mild conditions catalyzed by tetranuclear zinc cluster

(Chemical Equation Presented) A new catalytic transesterification promoted by a tetranuclear zinc cluster was developed. The mild reaction conditions enabled the reactions of various functionalized substrates to proceed in good to high yield. A large-scale reaction under solvent-free conditions proceeded with a low E-factor value (0.66), indicating the high environmental and economical advantage of the present catalysis.

Facile synthesis of polypyridine esters: A route to functionalized aldehydes

A wide range of ester-substituted oligopyridines, based on pyridine, 1,8-naphthyridine, 1,10-phenanthroline, 2,2'-bipyridine, and 2,2':6',6-terpyridine units, has been synthesized and fully characterized. The principal reaction involves the palladium(0)-catalyzed carboalkoxylation of the bromo-, chloro- or triflate-substituted pyridine unit with carbon monoxide in the presence of a primary alcohol as nucleophile and a tertiary amine as base. Monofunctionalization of disubstituted compounds is realized by reaction in ethanol under mild conditions (70 °C, 1 atm CO). Stepwise reduction of selected esters with sodium borohydride, followed by Swern oxidation, affords the corresponding carbaldehydes in good yield. Several products are reported for the first time. The synthetic methods reported herein represent a valuable approach to the large-scale preparation of ester-functionalized oligopyridines that can be subsequently transformed to the corresponding alcohols or acids. These procedures also provide a practical methodology to the rational design of ligands bearing different kinds of functionalities.