4175-78-4 Usage
Description
2,5-Dibromothiazole is a white to brown crystalline powder that serves as a versatile building block in material science and has applications in the pharmaceutical industry.
Uses
Used in Material Science:
2,5-Dibromothiazole is used as a building block for its unique chemical properties, which contribute to the development of novel materials with enhanced characteristics.
Used in Pharmaceutical Industry:
2,5-Dibromothiazole is used in the preparation of arylthiazolylpiperidine derivatives and analogs, which are crucial for modulating the production of survival motor neuron (SMN) protein. This application is significant for the development of therapeutic strategies targeting spinal muscular atrophy (SMA) and other related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 4175-78-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,7 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4175-78:
(6*4)+(5*1)+(4*7)+(3*5)+(2*7)+(1*8)=94
94 % 10 = 4
So 4175-78-4 is a valid CAS Registry Number.
InChI:InChI=1/C3HBr2NS/c4-2-1-6-3(5)7-2/h1H
4175-78-4Relevant articles and documents
COURSE OF BROMINATION OF THIAZOLE AND 2-METHYLTHIAZOLE
Gol'dfarb, Ya. L.,Gromova, G. P.,Belen'kii, L. I.
, p. 663 - 666 (1986)
Bromination of thiazole by bromine in the presence of aluminium chloride in neutral solvent or without solvent takes place at the 2-position.Such an orientation contradicts the traditional addition-cleavage mechanism, and agrees with the ylid mechanism of electrophilic substitution. 2-Methylthiazole brominates at the 5-position, and the reaction is impeded in the presence of aluminium chloride; this is due to heterocycle deactivation by complexation with the Lewis acid at the nitrogen atom.
